TGF-beta signal transduction: biology, function and therapy for diseases

TGF-beta signal transduction: biology, function and therapy for diseases

Abstract The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern in recent years to treat human diseases. This signal controls multiple cellular responses during embryonic development and tissue homeostasis through canonical and/or noncanonical signaling pathway...

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Bibliographic Details
Main Authors: Yan Tie, Fan Tang, Dandan Peng, Ye Zhang, Huashan Shi
Format: Article
Language:English
Published: Springer 2022-12-01
Series:Molecular Biomedicine
Subjects:
TGF-beta
Targeted therapy
Tumor microenvironment
Fibrosis
Anemia
Online Access:https://doi.org/10.1186/s43556-022-00109-9

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