Animal Coronavirus Diseases: Parallels with COVID-19 in Humans
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health glo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/8/1507 |
| _version_ | 1797521858569961472 |
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| author | Chao-Nan Lin Kuan Rong Chan Eng Eong Ooi Ming-Tang Chiou Minh Hoang Po-Ren Hsueh Peck Toung Ooi |
| author_facet | Chao-Nan Lin Kuan Rong Chan Eng Eong Ooi Ming-Tang Chiou Minh Hoang Po-Ren Hsueh Peck Toung Ooi |
| author_sort | Chao-Nan Lin |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health globally. Based on historical archives, the first coronavirus-related disease recorded was possibly animal-related, a case of feline infectious peritonitis described as early as 1912. Despite over a century of documented coronaviruses in animals, the global animal industry still suffers from outbreaks. Knowledge and experience handling animal coronaviruses provide a valuable tool to complement our understanding of the ongoing COVID-19 pandemic. In this review, we present an overview of coronaviruses, clinical signs, COVID-19 in animals, genome organization and recombination, immunopathogenesis, transmission, viral shedding, diagnosis, treatment, and prevention. By drawing parallels between COVID-19 in animals and humans, we provide perspectives on the pathophysiological mechanisms by which coronaviruses cause diseases in both animals and humans, providing a critical basis for the development of effective vaccines and therapeutics against these deadly viruses. |
| first_indexed | 2024-03-10T08:18:28Z |
| format | Article |
| id | doaj.art-4c93d275aefc468f8ac94b07b6b5cc54 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T08:18:28Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-4c93d275aefc468f8ac94b07b6b5cc542023-11-22T10:10:26ZengMDPI AGViruses1999-49152021-07-01138150710.3390/v13081507Animal Coronavirus Diseases: Parallels with COVID-19 in HumansChao-Nan Lin0Kuan Rong Chan1Eng Eong Ooi2Ming-Tang Chiou3Minh Hoang4Po-Ren Hsueh5Peck Toung Ooi6Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, TaiwanProgram in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857, SingaporeProgram in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857, SingaporeDepartment of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, TaiwanDepartment of Anatomy and Histology, College of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 100000, VietnamDepartments of Laboratory Medicine and Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung 404332, TaiwanFaculty of Veterinary Medicine, Universiti Putra Malaysia, UPM, Serdang 43400, Selangor, MalaysiaCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus in humans, has expanded globally over the past year. COVID-19 remains an important subject of intensive research owing to its huge impact on economic and public health globally. Based on historical archives, the first coronavirus-related disease recorded was possibly animal-related, a case of feline infectious peritonitis described as early as 1912. Despite over a century of documented coronaviruses in animals, the global animal industry still suffers from outbreaks. Knowledge and experience handling animal coronaviruses provide a valuable tool to complement our understanding of the ongoing COVID-19 pandemic. In this review, we present an overview of coronaviruses, clinical signs, COVID-19 in animals, genome organization and recombination, immunopathogenesis, transmission, viral shedding, diagnosis, treatment, and prevention. By drawing parallels between COVID-19 in animals and humans, we provide perspectives on the pathophysiological mechanisms by which coronaviruses cause diseases in both animals and humans, providing a critical basis for the development of effective vaccines and therapeutics against these deadly viruses.https://www.mdpi.com/1999-4915/13/8/1507animal coronavirusCOVID-19DIVAimmunopathogenesis |
| spellingShingle | Chao-Nan Lin Kuan Rong Chan Eng Eong Ooi Ming-Tang Chiou Minh Hoang Po-Ren Hsueh Peck Toung Ooi Animal Coronavirus Diseases: Parallels with COVID-19 in Humans Viruses animal coronavirus COVID-19 DIVA immunopathogenesis |
| title | Animal Coronavirus Diseases: Parallels with COVID-19 in Humans |
| title_full | Animal Coronavirus Diseases: Parallels with COVID-19 in Humans |
| title_fullStr | Animal Coronavirus Diseases: Parallels with COVID-19 in Humans |
| title_full_unstemmed | Animal Coronavirus Diseases: Parallels with COVID-19 in Humans |
| title_short | Animal Coronavirus Diseases: Parallels with COVID-19 in Humans |
| title_sort | animal coronavirus diseases parallels with covid 19 in humans |
| topic | animal coronavirus COVID-19 DIVA immunopathogenesis |
| url | https://www.mdpi.com/1999-4915/13/8/1507 |
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