Biodistribution and radiation dosimetry of [64Cu]copper dichloride: first-in-human study in healthy volunteers

Biodistribution and radiation dosimetry of [64Cu]copper dichloride: first-in-human study in healthy volunteers

Abstract Background In recent years, Copper-64 (T1/2 = 12.7 h) in the chemical form of copper dichloride ([64Cu]CuCl2) has been identified as a potential agent for PET imaging and radionuclide therapy targeting the human copper transporter 1, which is overexpressed in a variety of cancer cells. Limi...

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Main Authors: M.A. Avila-Rodriguez, C. Rios, J. Carrasco-Hernandez, J. C. Manrique-Arias, R. Martinez-Hernandez, F. O. García-Pérez, A. R. Jalilian, E. Martinez-Rodriguez, M. E. Romero-Piña, A. Diaz-Ruiz
Format: Article
Language:English
Published: SpringerOpen 2017-12-01
Series:EJNMMI Research
Subjects:
Copper-64
[64Cu]CuCl2
Copper biodistribution
Radiation dosimetry
Theranostics
Online Access:http://link.springer.com/article/10.1186/s13550-017-0346-4

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