Cell-free fat extract-loaded microneedles attenuate inflammation-induced apoptosis and mitochondrial damage in tendinopathy

Cell-free fat extract-loaded microneedles attenuate inflammation-induced apoptosis and mitochondrial damage in tendinopathy

Existing clinical treatments for tendinopathy mainly focus on reducing pain, whereas inhibiting or reversing disease progression remains challenging. Local therapeutic drugs, such as glucocorticoids, cause adverse effects on the metabolism of tendon tissues and injection-related complications. There...

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Bibliographic Details
Main Authors: Tianyou Kan, Zhaoyang Ran, Lin Sun, Xu Jiang, Lingli Hou, Yiqi Yang, Zhuoxuan Jia, Wenjie Zhang, Liao Wang, Mengning Yan, Kai Xie
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Materials Today Bio
Subjects:
Tendinopathy
Cell-free fat extract
Microneedle
Anti-apoptosis
Tumor necrosis factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001989

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