Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids

We present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortu...

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Bibliographic Details
Main Authors: G.I. Butel-Simoes, H. Kua, A. Safdar, M. Graham, T. Korman, Z. Meher-Homji
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Medical Mycology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753923000313
Description
Summary:We present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortunately a biopsy was performed and through histopathology & microbiological assessment a diagnosis of cryptococcal laryngitis was made. Treatment with 6 months of fluconazole resulted in clinical cure and resolution of symptoms. It is important to raise awareness of the risk of non-Candida fungal infections in patients on high dose corticosteroids, especially in the post covid era were steroids are more commonly prescribed.
ISSN:2211-7539