Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids
We present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-12-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753923000313 |
| _version_ | 1797398558321672192 |
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| author | G.I. Butel-Simoes H. Kua A. Safdar M. Graham T. Korman Z. Meher-Homji |
| author_facet | G.I. Butel-Simoes H. Kua A. Safdar M. Graham T. Korman Z. Meher-Homji |
| author_sort | G.I. Butel-Simoes |
| collection | DOAJ |
| description | We present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortunately a biopsy was performed and through histopathology & microbiological assessment a diagnosis of cryptococcal laryngitis was made. Treatment with 6 months of fluconazole resulted in clinical cure and resolution of symptoms. It is important to raise awareness of the risk of non-Candida fungal infections in patients on high dose corticosteroids, especially in the post covid era were steroids are more commonly prescribed. |
| first_indexed | 2024-03-09T01:28:11Z |
| format | Article |
| id | doaj.art-4ca7db6e4e1b47169108bbce7df13feb |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-03-09T01:28:11Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-4ca7db6e4e1b47169108bbce7df13feb2023-12-10T06:15:42ZengElsevierMedical Mycology Case Reports2211-75392023-12-0142100599Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroidsG.I. Butel-Simoes0H. Kua1A. Safdar2M. Graham3T. Korman4Z. Meher-Homji5Monash Infectious Diseases and Microbiology, Monash Health, Victoria, Australia; Corresponding author.Department of Anatomical Pathology, Monash Health, Victoria, AustraliaDepartment of Otolaryngology/ Head and Neck Surgery, Monash Health Victoria, AustraliaMonash Infectious Diseases and Microbiology, Monash Health, Victoria, Australia; Monash University, Clayton, Victoria, AustraliaMonash Infectious Diseases and Microbiology, Monash Health, Victoria, Australia; Monash University, Clayton, Victoria, AustraliaDepartment of Infectious Diseases, Latrobe Regional Hospital, Victoria, AustraliaWe present a case of laryngeal cryptococcosis caused by cryptococcosis neoformans var. grubii affecting a patient using excessive inhaled corticosteroids. The patient experienced symptoms for several months prior to specialist review and the visualization of a mass lesion by nasopharyngoscopy. Fortunately a biopsy was performed and through histopathology & microbiological assessment a diagnosis of cryptococcal laryngitis was made. Treatment with 6 months of fluconazole resulted in clinical cure and resolution of symptoms. It is important to raise awareness of the risk of non-Candida fungal infections in patients on high dose corticosteroids, especially in the post covid era were steroids are more commonly prescribed.http://www.sciencedirect.com/science/article/pii/S2211753923000313CryptococcosisLaryngitisInhaled corticosteroidDysphonia |
| spellingShingle | G.I. Butel-Simoes H. Kua A. Safdar M. Graham T. Korman Z. Meher-Homji Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids Medical Mycology Case Reports Cryptococcosis Laryngitis Inhaled corticosteroid Dysphonia |
| title | Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| title_full | Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| title_fullStr | Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| title_full_unstemmed | Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| title_short | Cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| title_sort | cryptococcal laryngitis in an immunocompetent asthmatic patient using inhaled corticosteroids |
| topic | Cryptococcosis Laryngitis Inhaled corticosteroid Dysphonia |
| url | http://www.sciencedirect.com/science/article/pii/S2211753923000313 |
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