Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe tw...
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Format: | Article |
Language: | English |
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SMC MEDIA SRL
2021-05-01
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Series: | European Journal of Case Reports in Internal Medicine |
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Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/2610 |
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author | Kadhim Al-banaa Alfarooq Alshaikhli Asal AL-Hareeri Mohammed Abdelhalim Alsadiq Al-Hillan Tejas Joshi |
author_facet | Kadhim Al-banaa Alfarooq Alshaikhli Asal AL-Hareeri Mohammed Abdelhalim Alsadiq Al-Hillan Tejas Joshi |
author_sort | Kadhim Al-banaa |
collection | DOAJ |
description | Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association. |
first_indexed | 2024-12-22T11:22:36Z |
format | Article |
id | doaj.art-4ca85c54a3a04b91b99be7f09b2f5d6e |
institution | Directory Open Access Journal |
issn | 2284-2594 |
language | English |
last_indexed | 2024-12-22T11:22:36Z |
publishDate | 2021-05-01 |
publisher | SMC MEDIA SRL |
record_format | Article |
series | European Journal of Case Reports in Internal Medicine |
spelling | doaj.art-4ca85c54a3a04b91b99be7f09b2f5d6e2022-12-21T18:27:50ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942021-05-0110.12890/2021_0026102226Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature ReviewKadhim Al-banaa0Alfarooq Alshaikhli1Asal AL-Hareeri2Mohammed Abdelhalim3Alsadiq Al-Hillan4Tejas Joshi5Department of Haemostasis and Thrombosis, University of California San Diego Health, San Diego, CA, USADepartment of Medicine, University of Texas/Rio Grande Valley, Edinburg, TX, USADepartment of Surgery, Harborview Medical Center, Seattle, WA, USADepartment of Medicine, Beaumont Hospital, Dearborn, MI, USADepartment of Gastroenterology, Beaumont Hospital, Royal Oak, MI, USA Department Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USAAntiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association.https://www.ejcrim.com/index.php/EJCRIM/article/view/2610antiphospholipid antibody syndromeapsarterial dissectionvasculopathystroke mimic |
spellingShingle | Kadhim Al-banaa Alfarooq Alshaikhli Asal AL-Hareeri Mohammed Abdelhalim Alsadiq Al-Hillan Tejas Joshi Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review European Journal of Case Reports in Internal Medicine antiphospholipid antibody syndrome aps arterial dissection vasculopathy stroke mimic |
title | Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review |
title_full | Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review |
title_fullStr | Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review |
title_full_unstemmed | Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review |
title_short | Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review |
title_sort | arterial dissection in antiphospholipid syndrome patients two case reports and a literature review |
topic | antiphospholipid antibody syndrome aps arterial dissection vasculopathy stroke mimic |
url | https://www.ejcrim.com/index.php/EJCRIM/article/view/2610 |
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