Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review

Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe tw...

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Main Authors: Kadhim Al-banaa, Alfarooq Alshaikhli, Asal AL-Hareeri, Mohammed Abdelhalim, Alsadiq Al-Hillan, Tejas Joshi
Format: Article
Language:English
Published: SMC MEDIA SRL 2021-05-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/2610
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author Kadhim Al-banaa
Alfarooq Alshaikhli
Asal AL-Hareeri
Mohammed Abdelhalim
Alsadiq Al-Hillan
Tejas Joshi
author_facet Kadhim Al-banaa
Alfarooq Alshaikhli
Asal AL-Hareeri
Mohammed Abdelhalim
Alsadiq Al-Hillan
Tejas Joshi
author_sort Kadhim Al-banaa
collection DOAJ
description Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association.
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spelling doaj.art-4ca85c54a3a04b91b99be7f09b2f5d6e2022-12-21T18:27:50ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942021-05-0110.12890/2021_0026102226Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature ReviewKadhim Al-banaa0Alfarooq Alshaikhli1Asal AL-Hareeri2Mohammed Abdelhalim3Alsadiq Al-Hillan4Tejas Joshi5Department of Haemostasis and Thrombosis, University of California San Diego Health, San Diego, CA, USADepartment of Medicine, University of Texas/Rio Grande Valley, Edinburg, TX, USADepartment of Surgery, Harborview Medical Center, Seattle, WA, USADepartment of Medicine, Beaumont Hospital, Dearborn, MI, USADepartment of Gastroenterology, Beaumont Hospital, Royal Oak, MI, USA Department Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USAAntiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association.https://www.ejcrim.com/index.php/EJCRIM/article/view/2610antiphospholipid antibody syndromeapsarterial dissectionvasculopathystroke mimic
spellingShingle Kadhim Al-banaa
Alfarooq Alshaikhli
Asal AL-Hareeri
Mohammed Abdelhalim
Alsadiq Al-Hillan
Tejas Joshi
Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
European Journal of Case Reports in Internal Medicine
antiphospholipid antibody syndrome
aps
arterial dissection
vasculopathy
stroke mimic
title Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
title_full Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
title_fullStr Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
title_full_unstemmed Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
title_short Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review
title_sort arterial dissection in antiphospholipid syndrome patients two case reports and a literature review
topic antiphospholipid antibody syndrome
aps
arterial dissection
vasculopathy
stroke mimic
url https://www.ejcrim.com/index.php/EJCRIM/article/view/2610
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AT mohammedabdelhalim arterialdissectioninantiphospholipidsyndromepatientstwocasereportsandaliteraturereview
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