Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features
Here, the authors analyze 4907 Circular Metagenome Assembled Genomes from human microbiomes and identify and characterize nearly 600 diverse genomes of crAss-like phages, finding two putative families with unusual genomic features, including high density of self-splicing introns and inteins.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21350-w |
| _version_ | 1818682938341982208 |
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| author | Natalya Yutin Sean Benler Sergei A. Shmakov Yuri I. Wolf Igor Tolstoy Mike Rayko Dmitry Antipov Pavel A. Pevzner Eugene V. Koonin |
| author_facet | Natalya Yutin Sean Benler Sergei A. Shmakov Yuri I. Wolf Igor Tolstoy Mike Rayko Dmitry Antipov Pavel A. Pevzner Eugene V. Koonin |
| author_sort | Natalya Yutin |
| collection | DOAJ |
| description | Here, the authors analyze 4907 Circular Metagenome Assembled Genomes from human microbiomes and identify and characterize nearly 600 diverse genomes of crAss-like phages, finding two putative families with unusual genomic features, including high density of self-splicing introns and inteins. |
| first_indexed | 2024-12-17T10:26:47Z |
| format | Article |
| id | doaj.art-4ca86dc23a1341df935e8c557a11ea34 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:26:47Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-4ca86dc23a1341df935e8c557a11ea342022-12-21T21:52:37ZengNature PortfolioNature Communications2041-17232021-02-0112111110.1038/s41467-021-21350-wAnalysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic featuresNatalya Yutin0Sean Benler1Sergei A. Shmakov2Yuri I. Wolf3Igor Tolstoy4Mike Rayko5Dmitry Antipov6Pavel A. Pevzner7Eugene V. Koonin8National Center for Biotechnology Information, National Library of MedicineNational Center for Biotechnology Information, National Library of MedicineNational Center for Biotechnology Information, National Library of MedicineNational Center for Biotechnology Information, National Library of MedicineNational Center for Biotechnology Information, National Library of MedicineCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State UniversityCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State UniversityDepartment of Computer Science and Engineering, University of California-San DiegoNational Center for Biotechnology Information, National Library of MedicineHere, the authors analyze 4907 Circular Metagenome Assembled Genomes from human microbiomes and identify and characterize nearly 600 diverse genomes of crAss-like phages, finding two putative families with unusual genomic features, including high density of self-splicing introns and inteins.https://doi.org/10.1038/s41467-021-21350-w |
| spellingShingle | Natalya Yutin Sean Benler Sergei A. Shmakov Yuri I. Wolf Igor Tolstoy Mike Rayko Dmitry Antipov Pavel A. Pevzner Eugene V. Koonin Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features Nature Communications |
| title | Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features |
| title_full | Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features |
| title_fullStr | Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features |
| title_full_unstemmed | Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features |
| title_short | Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features |
| title_sort | analysis of metagenome assembled viral genomes from the human gut reveals diverse putative crass like phages with unique genomic features |
| url | https://doi.org/10.1038/s41467-021-21350-w |
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