DNA topoisomerase 1α promotes transcriptional silencing of transposable elements through DNA methylation and histone lysine 9 dimethylation in Arabidopsis.

DNA topoisomerase 1α promotes transcriptional silencing of transposable elements through DNA methylation and histone lysine 9 dimethylation in Arabidopsis.

RNA-directed DNA methylation (RdDM) and histone H3 lysine 9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target transposable elements (TEs) and repeats to maintain genome stability in plants. RdDM is mediated by small and long noncoding RNAs produced by the plant-spe...

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Bibliographic Details
Main Authors: Thanh Theresa Dinh, Lei Gao, Xigang Liu, Dongming Li, Shengben Li, Yuanyuan Zhao, Michael O'Leary, Brandon Le, Robert J Schmitz, Pablo A Manavella, Shaofang Li, Detlef Weigel, Olga Pontes, Joseph R Ecker, Xuemei Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4080997?pdf=render

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