Adrenal stem cell niches are located between adrenal and renal capsules
The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment suitable for life and replication of adrenal st...
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| Format: | Article |
| Language: | English |
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Hygeia Press di Corridori Marinella
2016-08-01
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| Series: | Journal of Pediatric and Neonatal Individualized Medicine |
| Subjects: | |
| Online Access: | https://www.jpnim.com/index.php/jpnim/article/view/395 |
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| author | Eleonora Obinu Giorgia Locci Clara Gerosa Vassilios Fanos Laura Vinci Gavino Faa Rossano Ambu Cristina Loddo Elisabetta Coni Marco Angiolucci Claudia Fanni Daniela Fanni |
| author_facet | Eleonora Obinu Giorgia Locci Clara Gerosa Vassilios Fanos Laura Vinci Gavino Faa Rossano Ambu Cristina Loddo Elisabetta Coni Marco Angiolucci Claudia Fanni Daniela Fanni |
| author_sort | Eleonora Obinu |
| collection | DOAJ |
| description | The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment suitable for life and replication of adrenal stem cells.
Adrenal gland stem cells have the capacity to self-renew and generate functional differentiated daughter cells that replenish lost cells. Morphologically the adrenal stem cells appeared as small, polymorphic cells, closed together, with basophilic nucleus, located between adrenal and renal capsules. This study was mainly based on a morphological and immunohistochemical approach, particularly on characterization and localization of the multiple stem/progenitor cells that contribute to the development of the human adrenal gland.
Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future
Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordano |
| first_indexed | 2024-12-13T02:55:08Z |
| format | Article |
| id | doaj.art-4cb08f2debbe4a70993a932488f324b8 |
| institution | Directory Open Access Journal |
| issn | 2281-0692 |
| language | English |
| last_indexed | 2024-12-13T02:55:08Z |
| publishDate | 2016-08-01 |
| publisher | Hygeia Press di Corridori Marinella |
| record_format | Article |
| series | Journal of Pediatric and Neonatal Individualized Medicine |
| spelling | doaj.art-4cb08f2debbe4a70993a932488f324b82022-12-22T00:01:59ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922016-08-0152e050214e05021410.7363/050214332Adrenal stem cell niches are located between adrenal and renal capsulesEleonora Obinu0Giorgia Locci1Clara Gerosa2Vassilios Fanos3Laura Vinci4Gavino Faa5Rossano Ambu6Cristina Loddo7Elisabetta Coni8Marco Angiolucci9Claudia Fanni10Daniela Fanni11Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Section of Obstetrics and Gynecology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyThe human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment suitable for life and replication of adrenal stem cells. Adrenal gland stem cells have the capacity to self-renew and generate functional differentiated daughter cells that replenish lost cells. Morphologically the adrenal stem cells appeared as small, polymorphic cells, closed together, with basophilic nucleus, located between adrenal and renal capsules. This study was mainly based on a morphological and immunohistochemical approach, particularly on characterization and localization of the multiple stem/progenitor cells that contribute to the development of the human adrenal gland. Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordanohttps://www.jpnim.com/index.php/jpnim/article/view/395stem/progenitor cellsadrenal glandsadrenal gland stem cell nichesadrenal gland capsuleadrenal gland morphogenesisadrenal gland development |
| spellingShingle | Eleonora Obinu Giorgia Locci Clara Gerosa Vassilios Fanos Laura Vinci Gavino Faa Rossano Ambu Cristina Loddo Elisabetta Coni Marco Angiolucci Claudia Fanni Daniela Fanni Adrenal stem cell niches are located between adrenal and renal capsules Journal of Pediatric and Neonatal Individualized Medicine stem/progenitor cells adrenal glands adrenal gland stem cell niches adrenal gland capsule adrenal gland morphogenesis adrenal gland development |
| title | Adrenal stem cell niches are located between adrenal and renal capsules |
| title_full | Adrenal stem cell niches are located between adrenal and renal capsules |
| title_fullStr | Adrenal stem cell niches are located between adrenal and renal capsules |
| title_full_unstemmed | Adrenal stem cell niches are located between adrenal and renal capsules |
| title_short | Adrenal stem cell niches are located between adrenal and renal capsules |
| title_sort | adrenal stem cell niches are located between adrenal and renal capsules |
| topic | stem/progenitor cells adrenal glands adrenal gland stem cell niches adrenal gland capsule adrenal gland morphogenesis adrenal gland development |
| url | https://www.jpnim.com/index.php/jpnim/article/view/395 |
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