What makes the hepatitis C virus evolve?

Polymorphisms in the IFNL4 gene that affect both the presence and the form of the coded protein are associated with changes in the hepatitis C virus.

Bibliographic Details
Main Authors: Thomas R O'Brien, Rune Hartmann, Ludmila Prokunina-Olsson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/50148
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author Thomas R O'Brien
Rune Hartmann
Ludmila Prokunina-Olsson
author_facet Thomas R O'Brien
Rune Hartmann
Ludmila Prokunina-Olsson
author_sort Thomas R O'Brien
collection DOAJ
description Polymorphisms in the IFNL4 gene that affect both the presence and the form of the coded protein are associated with changes in the hepatitis C virus.
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spelling doaj.art-4cb1252a9b584cdcb7274dc27934959b2022-12-22T02:03:13ZengeLife Sciences Publications LtdeLife2050-084X2019-09-01810.7554/eLife.50148What makes the hepatitis C virus evolve?Thomas R O'Brien0https://orcid.org/0000-0003-0003-6065Rune Hartmann1https://orcid.org/0000-0003-1159-066XLudmila Prokunina-Olsson2https://orcid.org/0000-0002-9622-2091Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, United StatesDepartment of Molecular Biology, University of Aarhus, Aarhus, DenmarkLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, United StatesPolymorphisms in the IFNL4 gene that affect both the presence and the form of the coded protein are associated with changes in the hepatitis C virus.https://elifesciences.org/articles/50148Hepatitis Chost-pathogen interactionsinterferon-lambda 4innate immunity
spellingShingle Thomas R O'Brien
Rune Hartmann
Ludmila Prokunina-Olsson
What makes the hepatitis C virus evolve?
eLife
Hepatitis C
host-pathogen interactions
interferon-lambda 4
innate immunity
title What makes the hepatitis C virus evolve?
title_full What makes the hepatitis C virus evolve?
title_fullStr What makes the hepatitis C virus evolve?
title_full_unstemmed What makes the hepatitis C virus evolve?
title_short What makes the hepatitis C virus evolve?
title_sort what makes the hepatitis c virus evolve
topic Hepatitis C
host-pathogen interactions
interferon-lambda 4
innate immunity
url https://elifesciences.org/articles/50148
work_keys_str_mv AT thomasrobrien whatmakesthehepatitiscvirusevolve
AT runehartmann whatmakesthehepatitiscvirusevolve
AT ludmilaprokuninaolsson whatmakesthehepatitiscvirusevolve