Advances in upper airway cough syndrome

Upper airway cough syndrome (UACS), previously referred to as postnasal drip syndrome, is one of the most common causes of chronic cough. However, the pathogenesis of UACS/postnasal drip syndrome remains unclear, and physicians in countries throughout the world have different definitions and ways of...

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Main Authors: Li Yu, Xianghuai Xu, Hanjing Lv, Zhongmin Qiu
Format: Article
Language:English
Published: Wiley 2015-05-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X15000212
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author Li Yu
Xianghuai Xu
Hanjing Lv
Zhongmin Qiu
author_facet Li Yu
Xianghuai Xu
Hanjing Lv
Zhongmin Qiu
author_sort Li Yu
collection DOAJ
description Upper airway cough syndrome (UACS), previously referred to as postnasal drip syndrome, is one of the most common causes of chronic cough. However, the pathogenesis of UACS/postnasal drip syndrome remains unclear, and physicians in countries throughout the world have different definitions and ways of treating this disease. The various proposed pathogeneses of UACS include the early postnasal drip theory, subsequent chronic airway inflammation theory, and a recent sensory neural hypersensitivity theory. Additionally, some researchers suggest that UACS is a clinical phenotype of cough hypersensitivity syndrome. While the general principles involved in treating UACS are similar throughout the world, the specific details of treatment differ. This review summarizes the various definitions, pathogenic mechanisms, treatments, and other aspects of UACS, to aid clinicians in expanding their knowledge of how to diagnose and treat this syndrome.
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spelling doaj.art-4cb558b5b6454fedbaff65805077abfc2022-12-21T18:41:22ZengWileyKaohsiung Journal of Medical Sciences1607-551X2015-05-0131522322810.1016/j.kjms.2015.01.005Advances in upper airway cough syndromeLi YuXianghuai XuHanjing LvZhongmin QiuUpper airway cough syndrome (UACS), previously referred to as postnasal drip syndrome, is one of the most common causes of chronic cough. However, the pathogenesis of UACS/postnasal drip syndrome remains unclear, and physicians in countries throughout the world have different definitions and ways of treating this disease. The various proposed pathogeneses of UACS include the early postnasal drip theory, subsequent chronic airway inflammation theory, and a recent sensory neural hypersensitivity theory. Additionally, some researchers suggest that UACS is a clinical phenotype of cough hypersensitivity syndrome. While the general principles involved in treating UACS are similar throughout the world, the specific details of treatment differ. This review summarizes the various definitions, pathogenic mechanisms, treatments, and other aspects of UACS, to aid clinicians in expanding their knowledge of how to diagnose and treat this syndrome.http://www.sciencedirect.com/science/article/pii/S1607551X15000212Airway inflammationAtopic coughCough hypersensitivity syndromeSinobronchial syndromeUpper airway cough syndrome
spellingShingle Li Yu
Xianghuai Xu
Hanjing Lv
Zhongmin Qiu
Advances in upper airway cough syndrome
Kaohsiung Journal of Medical Sciences
Airway inflammation
Atopic cough
Cough hypersensitivity syndrome
Sinobronchial syndrome
Upper airway cough syndrome
title Advances in upper airway cough syndrome
title_full Advances in upper airway cough syndrome
title_fullStr Advances in upper airway cough syndrome
title_full_unstemmed Advances in upper airway cough syndrome
title_short Advances in upper airway cough syndrome
title_sort advances in upper airway cough syndrome
topic Airway inflammation
Atopic cough
Cough hypersensitivity syndrome
Sinobronchial syndrome
Upper airway cough syndrome
url http://www.sciencedirect.com/science/article/pii/S1607551X15000212
work_keys_str_mv AT liyu advancesinupperairwaycoughsyndrome
AT xianghuaixu advancesinupperairwaycoughsyndrome
AT hanjinglv advancesinupperairwaycoughsyndrome
AT zhongminqiu advancesinupperairwaycoughsyndrome