The interaction between miRNAs and hazardous materials
Toxic agents are broadly present in the environment, households, and workplaces. Contamination of food and drinking water with these agents results in entry of these materials to the body. The crosstalk between these agents and microRNAs (miRNAs) affects pathoetiology of several disorders. These age...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2023-12-01
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| Series: | Non-coding RNA Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468054023000458 |
| _version_ | 1797401678547255296 |
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| author | Soudeh Ghafouri-Fard Hamed Shoorei Shahram Dabiri Oskuei Bashdar Mahmud Hussen Snur Rasool Abdullah Mohammad Taheri Elena Jamali |
| author_facet | Soudeh Ghafouri-Fard Hamed Shoorei Shahram Dabiri Oskuei Bashdar Mahmud Hussen Snur Rasool Abdullah Mohammad Taheri Elena Jamali |
| author_sort | Soudeh Ghafouri-Fard |
| collection | DOAJ |
| description | Toxic agents are broadly present in the environment, households, and workplaces. Contamination of food and drinking water with these agents results in entry of these materials to the body. The crosstalk between these agents and microRNAs (miRNAs) affects pathoetiology of several disorders. These agents can influence the redox status, release of inflammatory cytokines and mitochondrial function. Altered expression of miRNA is involved in the dysregulation of several pathophysiological conditions and signaling pathways. These molecules are also implicated in the adaption to environmental stimuli. Thus, the interactions between miRNAs and toxic materials might participate in the hazardous effects of these materials in the body. This review describes the effects of the toxic materials on miRNAs and the consequences of these interactions on the human health. |
| first_indexed | 2024-03-09T02:13:33Z |
| format | Article |
| id | doaj.art-4cb5f421eb6a4d9ba97bce6ab8895fef |
| institution | Directory Open Access Journal |
| issn | 2468-0540 |
| language | English |
| last_indexed | 2024-03-09T02:13:33Z |
| publishDate | 2023-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Non-coding RNA Research |
| spelling | doaj.art-4cb5f421eb6a4d9ba97bce6ab8895fef2023-12-07T05:29:53ZengKeAi Communications Co., Ltd.Non-coding RNA Research2468-05402023-12-0184507519The interaction between miRNAs and hazardous materialsSoudeh Ghafouri-Fard0Hamed Shoorei1Shahram Dabiri Oskuei2Bashdar Mahmud Hussen3Snur Rasool Abdullah4Mohammad Taheri5Elena Jamali6Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Anatomical Sciences, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran; Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, IranClinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Clinical Analysis, College of Pharmacy, Hawler Medical University, Kurdistan Region, IraqMedical Laboratory Science, Lebanese French University, Kurdistan Region, Erbil, IraqInstitute of Human Genetics, Jena University Hospital, Jena, Germany; Urology and Nephrology Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Corresponding author. Urology and Nephrology Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Corresponding author.Toxic agents are broadly present in the environment, households, and workplaces. Contamination of food and drinking water with these agents results in entry of these materials to the body. The crosstalk between these agents and microRNAs (miRNAs) affects pathoetiology of several disorders. These agents can influence the redox status, release of inflammatory cytokines and mitochondrial function. Altered expression of miRNA is involved in the dysregulation of several pathophysiological conditions and signaling pathways. These molecules are also implicated in the adaption to environmental stimuli. Thus, the interactions between miRNAs and toxic materials might participate in the hazardous effects of these materials in the body. This review describes the effects of the toxic materials on miRNAs and the consequences of these interactions on the human health.http://www.sciencedirect.com/science/article/pii/S2468054023000458miRNAHazardous materialCancer |
| spellingShingle | Soudeh Ghafouri-Fard Hamed Shoorei Shahram Dabiri Oskuei Bashdar Mahmud Hussen Snur Rasool Abdullah Mohammad Taheri Elena Jamali The interaction between miRNAs and hazardous materials Non-coding RNA Research miRNA Hazardous material Cancer |
| title | The interaction between miRNAs and hazardous materials |
| title_full | The interaction between miRNAs and hazardous materials |
| title_fullStr | The interaction between miRNAs and hazardous materials |
| title_full_unstemmed | The interaction between miRNAs and hazardous materials |
| title_short | The interaction between miRNAs and hazardous materials |
| title_sort | interaction between mirnas and hazardous materials |
| topic | miRNA Hazardous material Cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2468054023000458 |
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