Catheter ablation in combined procedures is associated with residual leaks
ObjectivesTo compare patients with atrial fibrillation (AF) undergoing left atrial appendage closure (LAAC) with catheter ablation (CA) and those without CA.BackgroundThe CA of AF may cause ridge edema, which may affect the safety of LAAC.MethodsPatients with AF (N = 98) who underwent LAAC (combined...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1091049/full |
| _version_ | 1797937959313342464 |
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| author | Xuefeng Zhu Wenjing Li Hongxia Chu Lin Zhong Chunxiao Wang Jianping Li Pingping Liang Lihong Wang Lei Shi |
| author_facet | Xuefeng Zhu Wenjing Li Hongxia Chu Lin Zhong Chunxiao Wang Jianping Li Pingping Liang Lihong Wang Lei Shi |
| author_sort | Xuefeng Zhu |
| collection | DOAJ |
| description | ObjectivesTo compare patients with atrial fibrillation (AF) undergoing left atrial appendage closure (LAAC) with catheter ablation (CA) and those without CA.BackgroundThe CA of AF may cause ridge edema, which may affect the safety of LAAC.MethodsPatients with AF (N = 98) who underwent LAAC (combined CA + LAAC procedure group; N = 51) or alone (LAAC group; N = 47) received pre-procedural, intra-procedural, and 6 week post-procedural transesophageal echocardiography (TEE). The depth and ostial diameter of LAA, device compression, residual leak, and ridge thickness were evaluated in the patients who had undergone combined and alone procedures, as well as images of LAA and primary clinical characteristics.ResultsA residual leak was identified in 27 patients at 6 weeks after implantation by TEE (19 in the combined procedures group and eight in the alone group; p = 0.04). The combined procedure group had a significantly higher rate of a new residual leak than the alone group (25.5 vs. 8.5%; p = 0.03). Meanwhile, compared with at the time of implant, a smaller amount of device compression ratio was significant after 6 weeks (22.44 ± 3.90 vs. 19.59 ± 5.39; p = 0.03). There was no significant difference between both groups in all-cause mortality, cardiovascular mortality, and TIA/stroke/system embolism.ConclusionThe combined procedures of CA and LAAC for AF are feasible and safe; however, during the follow-up period, we found that the resolution of ridge edema caused by CA might cause an increased residual leak and a smaller device compression ratio. |
| first_indexed | 2024-04-10T18:53:32Z |
| format | Article |
| id | doaj.art-4cb695bd4f1648bb9dcc4cada1d44ccc |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T18:53:32Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-4cb695bd4f1648bb9dcc4cada1d44ccc2023-02-01T05:09:53ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-02-01910.3389/fcvm.2022.10910491091049Catheter ablation in combined procedures is associated with residual leaksXuefeng Zhu0Wenjing Li1Hongxia Chu2Lin Zhong3Chunxiao Wang4Jianping Li5Pingping Liang6Lihong Wang7Lei Shi8Department of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDoppler Ultrasonic Department, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDepartment of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDepartment of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDepartment of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDoppler Ultrasonic Department, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDepartment of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDoppler Ultrasonic Department, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaDoppler Ultrasonic Department, Yantai Yuhuangding Hospital, Yantai, Shandong, ChinaObjectivesTo compare patients with atrial fibrillation (AF) undergoing left atrial appendage closure (LAAC) with catheter ablation (CA) and those without CA.BackgroundThe CA of AF may cause ridge edema, which may affect the safety of LAAC.MethodsPatients with AF (N = 98) who underwent LAAC (combined CA + LAAC procedure group; N = 51) or alone (LAAC group; N = 47) received pre-procedural, intra-procedural, and 6 week post-procedural transesophageal echocardiography (TEE). The depth and ostial diameter of LAA, device compression, residual leak, and ridge thickness were evaluated in the patients who had undergone combined and alone procedures, as well as images of LAA and primary clinical characteristics.ResultsA residual leak was identified in 27 patients at 6 weeks after implantation by TEE (19 in the combined procedures group and eight in the alone group; p = 0.04). The combined procedure group had a significantly higher rate of a new residual leak than the alone group (25.5 vs. 8.5%; p = 0.03). Meanwhile, compared with at the time of implant, a smaller amount of device compression ratio was significant after 6 weeks (22.44 ± 3.90 vs. 19.59 ± 5.39; p = 0.03). There was no significant difference between both groups in all-cause mortality, cardiovascular mortality, and TIA/stroke/system embolism.ConclusionThe combined procedures of CA and LAAC for AF are feasible and safe; however, during the follow-up period, we found that the resolution of ridge edema caused by CA might cause an increased residual leak and a smaller device compression ratio.https://www.frontiersin.org/articles/10.3389/fcvm.2022.1091049/fullatrial fibrillationleft atrial appendage closureresidual leakcatheter ablationwatchman |
| spellingShingle | Xuefeng Zhu Wenjing Li Hongxia Chu Lin Zhong Chunxiao Wang Jianping Li Pingping Liang Lihong Wang Lei Shi Catheter ablation in combined procedures is associated with residual leaks Frontiers in Cardiovascular Medicine atrial fibrillation left atrial appendage closure residual leak catheter ablation watchman |
| title | Catheter ablation in combined procedures is associated with residual leaks |
| title_full | Catheter ablation in combined procedures is associated with residual leaks |
| title_fullStr | Catheter ablation in combined procedures is associated with residual leaks |
| title_full_unstemmed | Catheter ablation in combined procedures is associated with residual leaks |
| title_short | Catheter ablation in combined procedures is associated with residual leaks |
| title_sort | catheter ablation in combined procedures is associated with residual leaks |
| topic | atrial fibrillation left atrial appendage closure residual leak catheter ablation watchman |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1091049/full |
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