SDF-1/CXCR4 Augments the Therapeutic Effect of Bone Marrow Mesenchymal Stem Cells in the Treatment of Lipopolysaccharide-Induced Liver Injury by Promoting Their Migration Through PI3K/Akt Signaling Pathway

SDF-1/CXCR4 Augments the Therapeutic Effect of Bone Marrow Mesenchymal Stem Cells in the Treatment of Lipopolysaccharide-Induced Liver Injury by Promoting Their Migration Through PI3K/Akt Signaling Pathway

Mesenchymal stem cells (MSCs) are thought to have great potential in the therapy of acute liver injury. It is possible that these cells may be regulated by the stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor-4 (CXCR4) signaling axis, which has been shown to promote stem cells migration...

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Bibliographic Details
Main Authors: Guanghui Xiu, Xiuling Li, Yunyu Yin, Jintao Li, Bingqin Li, Xianzhong Chen, Ping Liu, Jie Sun, Bin Ling
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720929992

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