Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials
Abstract Purpose The clinical outcomes of using a zero-profile for anterior cervical decompression and fusion were evaluated by comparison with anterior cervical plates. Methods All of the comparative studies published in the PubMed, Cochrane Library, Medline, Web of Science, EBSOChost, and EMBASE d...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-01-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-022-02940-w |
| _version_ | 1798034315143020544 |
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| author | Tingxin Zhang Nana Guo Gang Gao Hao Liu Yanhong Li Feng Gao Qingxin Zhang Xiaoyang Tao Wupeng Yang Yongjiang Wang |
| author_facet | Tingxin Zhang Nana Guo Gang Gao Hao Liu Yanhong Li Feng Gao Qingxin Zhang Xiaoyang Tao Wupeng Yang Yongjiang Wang |
| author_sort | Tingxin Zhang |
| collection | DOAJ |
| description | Abstract Purpose The clinical outcomes of using a zero-profile for anterior cervical decompression and fusion were evaluated by comparison with anterior cervical plates. Methods All of the comparative studies published in the PubMed, Cochrane Library, Medline, Web of Science, EBSOChost, and EMBASE databases as of 1 October 2021 were included. All outcomes were analysed using Review Manager 5.4. Results Seven randomized controlled studies were included with a total of 528 patients, and all studies were randomized controlled studies. The meta-analysis outcomes indicated that the use of zero-profile fixation for anterior cervical decompression and fusion was better than anterior cervical plate fixation regarding the incidence of postoperative dysphagia (P < 0.05), adjacent-level ossification (P < 0.05), and operational time (P < 0.05). However, there were no statistically significant differences in intraoperative blood loss, Visual Analogue Scale, Neck Disability Index, or Japanese Orthopaedic Association scale (all P > 0.05) between the zero-profile and anterior cervical plate groups. Conclusions The systematic review and meta-analysis indicated that zero-profile and anterior cervical plates could result in good postoperative outcomes in anterior cervical decompression and fusion. No significant differences were found in intraoperative blood loss, Visual Analogue Scale, Neck Disability Index, or Japanese Orthopaedic Association scale. However, the zero-profile is superior to the anterior cervical plate in the following measures: incidence of postoperative dysphagia, adjacent-level ossification, and operational time. PROSPERO registration CRD42021278214. |
| first_indexed | 2024-04-11T20:42:28Z |
| format | Article |
| id | doaj.art-4cb9b21e0a0c4a0eb166e98b6b2dc7df |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-11T20:42:28Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-4cb9b21e0a0c4a0eb166e98b6b2dc7df2022-12-22T04:04:09ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2022-01-011711910.1186/s13018-022-02940-wComparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trialsTingxin Zhang0Nana Guo1Gang Gao2Hao Liu3Yanhong Li4Feng Gao5Qingxin Zhang6Xiaoyang Tao7Wupeng Yang8Yongjiang Wang9Department of Orthopedics, Ordos Central HospitalCritical Care Medicine, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalDepartment of Orthopedics, Ordos Central HospitalAbstract Purpose The clinical outcomes of using a zero-profile for anterior cervical decompression and fusion were evaluated by comparison with anterior cervical plates. Methods All of the comparative studies published in the PubMed, Cochrane Library, Medline, Web of Science, EBSOChost, and EMBASE databases as of 1 October 2021 were included. All outcomes were analysed using Review Manager 5.4. Results Seven randomized controlled studies were included with a total of 528 patients, and all studies were randomized controlled studies. The meta-analysis outcomes indicated that the use of zero-profile fixation for anterior cervical decompression and fusion was better than anterior cervical plate fixation regarding the incidence of postoperative dysphagia (P < 0.05), adjacent-level ossification (P < 0.05), and operational time (P < 0.05). However, there were no statistically significant differences in intraoperative blood loss, Visual Analogue Scale, Neck Disability Index, or Japanese Orthopaedic Association scale (all P > 0.05) between the zero-profile and anterior cervical plate groups. Conclusions The systematic review and meta-analysis indicated that zero-profile and anterior cervical plates could result in good postoperative outcomes in anterior cervical decompression and fusion. No significant differences were found in intraoperative blood loss, Visual Analogue Scale, Neck Disability Index, or Japanese Orthopaedic Association scale. However, the zero-profile is superior to the anterior cervical plate in the following measures: incidence of postoperative dysphagia, adjacent-level ossification, and operational time. PROSPERO registration CRD42021278214.https://doi.org/10.1186/s13018-022-02940-wZero-profileAnterior cervical plateAnterior cervical decompression and fusionMeta-analysisSystematic review |
| spellingShingle | Tingxin Zhang Nana Guo Gang Gao Hao Liu Yanhong Li Feng Gao Qingxin Zhang Xiaoyang Tao Wupeng Yang Yongjiang Wang Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials Journal of Orthopaedic Surgery and Research Zero-profile Anterior cervical plate Anterior cervical decompression and fusion Meta-analysis Systematic review |
| title | Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials |
| title_full | Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials |
| title_short | Comparison of outcomes between Zero-p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion: a systematic review and meta-analysis of randomized controlled trials |
| title_sort | comparison of outcomes between zero p implant and anterior cervical plate interbody fusion systems for anterior cervical decompression and fusion a systematic review and meta analysis of randomized controlled trials |
| topic | Zero-profile Anterior cervical plate Anterior cervical decompression and fusion Meta-analysis Systematic review |
| url | https://doi.org/10.1186/s13018-022-02940-w |
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