Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation
Background: The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective: To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods: A total of 240 patients presen...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Springer
2018-08-01
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| Series: | Egyptian Journal of Critical Care Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S209073031830001X |
| _version_ | 1797282485073084416 |
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| author | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek |
| author_facet | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek |
| author_sort | Hazem El-Akabawy |
| collection | DOAJ |
| description | Background: The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective: To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods: A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: group A; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and group B; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. Group A patients subdivided into subgroup I, patients with improvement of the IMR; and subgroup II, patients with no improvement of IMR. Results: Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization. Conclusion: Successful total revascularization by early PCI improve IMR degree. Keywords: Ischemic mitral regurge, Total revascularization, Acute coronary syndrome, Percutaneous coronary intervention, Myocardial infarction, Echocardiography |
| first_indexed | 2024-03-07T17:13:45Z |
| format | Article |
| id | doaj.art-4cba531d58174d8b9df0fa369a47b905 |
| institution | Directory Open Access Journal |
| issn | 2090-7303 |
| language | English |
| last_indexed | 2024-03-07T17:13:45Z |
| publishDate | 2018-08-01 |
| publisher | Springer |
| record_format | Article |
| series | Egyptian Journal of Critical Care Medicine |
| spelling | doaj.art-4cba531d58174d8b9df0fa369a47b9052024-03-02T23:38:07ZengSpringerEgyptian Journal of Critical Care Medicine2090-73032018-08-01622531Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitationHazem El-Akabawy0Hamdy Abdul Azeem1EL-Shazly Abdul Khalek2Critical Care Medicine, Cairo University, Cairo, Egypt; Corresponding author at: Critical Care Medicine Department, Kasr Alaini, Cairo University, 4-Mahmoud Samy Barody street, Alharam street, Cairo, Egypt.Cardiology Department, Al Azhar University, Cairo, EgyptCardiology Department, Al Azhar University, Cairo, EgyptBackground: The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective: To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods: A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: group A; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and group B; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. Group A patients subdivided into subgroup I, patients with improvement of the IMR; and subgroup II, patients with no improvement of IMR. Results: Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization. Conclusion: Successful total revascularization by early PCI improve IMR degree. Keywords: Ischemic mitral regurge, Total revascularization, Acute coronary syndrome, Percutaneous coronary intervention, Myocardial infarction, Echocardiographyhttp://www.sciencedirect.com/science/article/pii/S209073031830001X |
| spellingShingle | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation Egyptian Journal of Critical Care Medicine |
| title | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_full | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_fullStr | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_full_unstemmed | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_short | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_sort | short term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| url | http://www.sciencedirect.com/science/article/pii/S209073031830001X |
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