Possible interaction of warfarin with peppermint herbal tea: a case report
Herbal medicine is usually safe and popular in Iranian communities. Peppermint herbal products may interact with warfarin, which is an essential lifelong drug used in patients with prosthetic heart valves. Herein, we report a case of possible interaction between warfarin and peppermint herbal tea.We...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2017-05-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_7899_0fd14035182c4803e7b35d7ec425c8bb.pdf |
| _version_ | 1797976068521459712 |
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| author | Aliasghar Moeinipour Mohamad Abbassi Teshnizi Babak Manafi Hadi Yavari Yasamin Moeinipour Hamid Hoseinikhah |
| author_facet | Aliasghar Moeinipour Mohamad Abbassi Teshnizi Babak Manafi Hadi Yavari Yasamin Moeinipour Hamid Hoseinikhah |
| author_sort | Aliasghar Moeinipour |
| collection | DOAJ |
| description | Herbal medicine is usually safe and popular in Iranian communities. Peppermint herbal products may interact with warfarin, which is an essential lifelong drug used in patients with prosthetic heart valves. Herein, we report a case of possible interaction between warfarin and peppermint herbal tea.We described a 68-year-old woman who was on warfarin treatment due to bileaflet mechanical aortic valve, and mitral valve replacement presented with severe dyspnea in the setting of large obstructive prosthetic mitral valve thrombosis diagnosed by echocardiography. Therefore, cardiac surgery was conducted in the emergent setting. Warfarin was started the day after the procedure. She developed melena with a volatile and elevated international normalized ratio (INR) of 4.8 and prothrombin time > 30 s on the 7th post-operation day. She reported no changes in drug or dietary habits except for drinking high amounts of peppermint tea the day before. After the discontinuation of warfarin and medical consultation for gastrointestinal bleeding, the INR level decreased to 1.8 within two days.Consumption of peppermint herbal products are usually safe; however, caution should be taken with patients under warfarin treatment. Full disclosure for patients on anticoagulant treatment is necessary before discharge and during clinical follow-up |
| first_indexed | 2024-04-11T04:45:28Z |
| format | Article |
| id | doaj.art-4cba8d1d80d4422aafb060c59c652837 |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:45:28Z |
| publishDate | 2017-05-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-4cba8d1d80d4422aafb060c59c6528372022-12-27T13:09:14ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922017-05-0142838610.22038/rcm.2016.78997899Possible interaction of warfarin with peppermint herbal tea: a case reportAliasghar Moeinipour0Mohamad Abbassi Teshnizi1Babak Manafi2Hadi Yavari3Yasamin Moeinipour4Hamid Hoseinikhah5Department of Cardiovascular Surgery, Atherosclerosis Prevention Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Cardiovascular Surgery, Atherosclerosis Prevention Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Cardiovascular Surgery, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Head Nursing of Cardiac Surgery Operation Room, Imam Reza Hospital, Mashhad, Iran.Medical Student, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Cardiovascular Surgery, Atherosclerosis Prevention Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Herbal medicine is usually safe and popular in Iranian communities. Peppermint herbal products may interact with warfarin, which is an essential lifelong drug used in patients with prosthetic heart valves. Herein, we report a case of possible interaction between warfarin and peppermint herbal tea.We described a 68-year-old woman who was on warfarin treatment due to bileaflet mechanical aortic valve, and mitral valve replacement presented with severe dyspnea in the setting of large obstructive prosthetic mitral valve thrombosis diagnosed by echocardiography. Therefore, cardiac surgery was conducted in the emergent setting. Warfarin was started the day after the procedure. She developed melena with a volatile and elevated international normalized ratio (INR) of 4.8 and prothrombin time > 30 s on the 7th post-operation day. She reported no changes in drug or dietary habits except for drinking high amounts of peppermint tea the day before. After the discontinuation of warfarin and medical consultation for gastrointestinal bleeding, the INR level decreased to 1.8 within two days.Consumption of peppermint herbal products are usually safe; however, caution should be taken with patients under warfarin treatment. Full disclosure for patients on anticoagulant treatment is necessary before discharge and during clinical follow-uphttps://rcm.mums.ac.ir/article_7899_0fd14035182c4803e7b35d7ec425c8bb.pdfanticoagulant drugsherbal medicinewarfaring interaction |
| spellingShingle | Aliasghar Moeinipour Mohamad Abbassi Teshnizi Babak Manafi Hadi Yavari Yasamin Moeinipour Hamid Hoseinikhah Possible interaction of warfarin with peppermint herbal tea: a case report Reviews in Clinical Medicine anticoagulant drugs herbal medicine warfaring interaction |
| title | Possible interaction of warfarin with peppermint herbal tea: a case report |
| title_full | Possible interaction of warfarin with peppermint herbal tea: a case report |
| title_fullStr | Possible interaction of warfarin with peppermint herbal tea: a case report |
| title_full_unstemmed | Possible interaction of warfarin with peppermint herbal tea: a case report |
| title_short | Possible interaction of warfarin with peppermint herbal tea: a case report |
| title_sort | possible interaction of warfarin with peppermint herbal tea a case report |
| topic | anticoagulant drugs herbal medicine warfaring interaction |
| url | https://rcm.mums.ac.ir/article_7899_0fd14035182c4803e7b35d7ec425c8bb.pdf |
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