Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report
Twin pregnancies with a complete hydatidiform mole and a coexisting live fetus are rare. The incidence is estimated to be 1 in 20,000-100,000 pregnancies. Prenatal diagnosis can be made with ultrasound findings, abnormally elevated β-hCG levels, and fetal karyotype. There are various complications f...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323004296 |
| _version_ | 1797737978197442560 |
|---|---|
| author | Danijel Bursać, MD, PhD Marta Horvat, MD Diana Culej, MD Dejana Lučić, MD Lovro Marinović, MD Jasenka Zmijanac Partl, MD, PhD |
| author_facet | Danijel Bursać, MD, PhD Marta Horvat, MD Diana Culej, MD Dejana Lučić, MD Lovro Marinović, MD Jasenka Zmijanac Partl, MD, PhD |
| author_sort | Danijel Bursać, MD, PhD |
| collection | DOAJ |
| description | Twin pregnancies with a complete hydatidiform mole and a coexisting live fetus are rare. The incidence is estimated to be 1 in 20,000-100,000 pregnancies. Prenatal diagnosis can be made with ultrasound findings, abnormally elevated β-hCG levels, and fetal karyotype. There are various complications following these pregnancies which include hyperemesis gravidarum, vaginal bleeding, spontaneous abortion, pre-eclampsia, intrauterine growth retardation, preterm delivery, and persistent trophoblastic disease. We report an interesting case of twin pregnancy consisting of a complete hydatidiform mole and a normal fetus achieved with in-vitro fertilization in a primary infertile couple. Suspicion of molar pregnancy was made on ultrasound examination, but the couple refused other prenatal testing and wanted to continue the pregnancy. Although the pregnancy was at high risk because of the patient's age and complications associated with a molar pregnancy, a vigorous female baby was delivered at term. The purpose of this report is to present a case of a rare obstetric condition, give evidence that gestational trophoblastic disease is occurring more commonly in multiple gestations and in-vitro fertilization pregnancies, and highlight the importance of ultrasound in prenatal diagnostics and monitoring of high-risk pregnancies. |
| first_indexed | 2024-03-12T13:37:15Z |
| format | Article |
| id | doaj.art-4cbf83e08b57461387b88a137694d365 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-12T13:37:15Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-4cbf83e08b57461387b88a137694d3652023-08-24T04:34:26ZengElsevierRadiology Case Reports1930-04332023-10-01181034103413Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case reportDanijel Bursać, MD, PhD0Marta Horvat, MD1Diana Culej, MD2Dejana Lučić, MD3Lovro Marinović, MD4Jasenka Zmijanac Partl, MD, PhD5Department of Obstetrics and Gynecology, University Hospital Merkur, Zagreb, Croatia; Department of Nursing, University North, Varaždin, CroatiaHealth Center Zagreb West, Zagreb, Croatia; Corresponding author.Department of Obstetrics and Gynecology, University Hospital Merkur, Zagreb, CroatiaDepartment of Obstetrics and Gynecology, Polyclinic “Vaš Pregled”, Zagreb, CroatiaDepartment of Pathology and Cytology, University Hospital Merkur, Zagreb, CroatiaDepartment of Obstetrics and Gynecology, University Hospital Merkur, Zagreb, CroatiaTwin pregnancies with a complete hydatidiform mole and a coexisting live fetus are rare. The incidence is estimated to be 1 in 20,000-100,000 pregnancies. Prenatal diagnosis can be made with ultrasound findings, abnormally elevated β-hCG levels, and fetal karyotype. There are various complications following these pregnancies which include hyperemesis gravidarum, vaginal bleeding, spontaneous abortion, pre-eclampsia, intrauterine growth retardation, preterm delivery, and persistent trophoblastic disease. We report an interesting case of twin pregnancy consisting of a complete hydatidiform mole and a normal fetus achieved with in-vitro fertilization in a primary infertile couple. Suspicion of molar pregnancy was made on ultrasound examination, but the couple refused other prenatal testing and wanted to continue the pregnancy. Although the pregnancy was at high risk because of the patient's age and complications associated with a molar pregnancy, a vigorous female baby was delivered at term. The purpose of this report is to present a case of a rare obstetric condition, give evidence that gestational trophoblastic disease is occurring more commonly in multiple gestations and in-vitro fertilization pregnancies, and highlight the importance of ultrasound in prenatal diagnostics and monitoring of high-risk pregnancies.http://www.sciencedirect.com/science/article/pii/S1930043323004296Twin pregnancyComplete hydatidiform moleGestational trophoblastic diseaseUltrasonography |
| spellingShingle | Danijel Bursać, MD, PhD Marta Horvat, MD Diana Culej, MD Dejana Lučić, MD Lovro Marinović, MD Jasenka Zmijanac Partl, MD, PhD Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report Radiology Case Reports Twin pregnancy Complete hydatidiform mole Gestational trophoblastic disease Ultrasonography |
| title | Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report |
| title_full | Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report |
| title_fullStr | Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report |
| title_full_unstemmed | Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report |
| title_short | Prenatal diagnosis and management of pregnancy complicated by a coexisting mole: A case report |
| title_sort | prenatal diagnosis and management of pregnancy complicated by a coexisting mole a case report |
| topic | Twin pregnancy Complete hydatidiform mole Gestational trophoblastic disease Ultrasonography |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323004296 |
| work_keys_str_mv | AT danijelbursacmdphd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport AT martahorvatmd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport AT dianaculejmd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport AT dejanalucicmd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport AT lovromarinovicmd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport AT jasenkazmijanacpartlmdphd prenataldiagnosisandmanagementofpregnancycomplicatedbyacoexistingmoleacasereport |