Duration differences of corticostriatal responses in striatal projection neurons depend on calcium activated potassium currents

Duration differences of corticostriatal responses in striatal projection neurons depend on calcium activated potassium currents

The firing of striatal projection neurons (SPNs) exhibits afterhyperpolarizing potentials (AHPs) that determine discharge frequency. They are in part generated by Ca2+-activated K+-currents involving BK and SK components. It has previously been shown that suprathreshold corticostriatal responses are...

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Bibliographic Details
Main Authors: Mario Alberto Arias-García, Dagoberto eTapia, Edén eFlores-Barrera, Jesús Esteban Pérez-Ortega, Jose eBargas, Elvira eGalarraga
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Striatum
SK channels
BK channels
Synaptic integration
corticostriatal pathway
Medium spiny neurons
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00063/full

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