Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis
<p>Abstract</p> <p>Lymphatic Filariasis (LF) is targeted for elimination by the Global Programme for the Elimination of Lymphatic Filariasis (GPELF). The strategy adopted is based on the density dependent phenomenon of Facilitation, which hypothesizes that in an area where the vect...
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| Format: | Article |
| Language: | English |
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BMC
2012-11-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | http://www.parasitesandvectors.com/content/5/1/259 |
| _version_ | 1828744453575147520 |
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| author | de Souza Dziedzom K Koudou Benjamin Kelly-Hope Louise A Wilson Michael D Bockarie Moses J Boakye Daniel A |
| author_facet | de Souza Dziedzom K Koudou Benjamin Kelly-Hope Louise A Wilson Michael D Bockarie Moses J Boakye Daniel A |
| author_sort | de Souza Dziedzom K |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Lymphatic Filariasis (LF) is targeted for elimination by the Global Programme for the Elimination of Lymphatic Filariasis (GPELF). The strategy adopted is based on the density dependent phenomenon of Facilitation, which hypothesizes that in an area where the vector species transmitting <it>Wuchereria bancrofti</it> are <it>Anopheles</it> mosquitoes, it is feasible to eliminate LF using Mass Drug Administration (MDA) because of the inability of <it>Anopheles</it> species to transmit low-density microfilaraemia. Even though earlier studies have shown <it>Anopheles species</it> can exhibit the process of Facilitation in West Africa, observations point towards the process of Limitation in certain areas, in which case vector control is recommended. Studies on <it>Anopheles</it> species in West Africa have also shown genetic differentiation, cryptic taxa and speciation, insecticide resistance and the existence of molecular and chromosomal forms, all of which could influence the vectorial capacity of the mosquitoes and ultimately the elimination goal. This paper outlines the uniqueness of LF vectors in West Africa and the challenges it poses to the 2020 elimination goal, based on the current MDA strategies.</p> |
| first_indexed | 2024-04-13T02:49:25Z |
| format | Article |
| id | doaj.art-4cc5ff7e7e8548309a4a28c47839684a |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-04-13T02:49:25Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-4cc5ff7e7e8548309a4a28c47839684a2022-12-22T03:05:54ZengBMCParasites & Vectors1756-33052012-11-015125910.1186/1756-3305-5-259Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasisde Souza Dziedzom KKoudou BenjaminKelly-Hope Louise AWilson Michael DBockarie Moses JBoakye Daniel A<p>Abstract</p> <p>Lymphatic Filariasis (LF) is targeted for elimination by the Global Programme for the Elimination of Lymphatic Filariasis (GPELF). The strategy adopted is based on the density dependent phenomenon of Facilitation, which hypothesizes that in an area where the vector species transmitting <it>Wuchereria bancrofti</it> are <it>Anopheles</it> mosquitoes, it is feasible to eliminate LF using Mass Drug Administration (MDA) because of the inability of <it>Anopheles</it> species to transmit low-density microfilaraemia. Even though earlier studies have shown <it>Anopheles species</it> can exhibit the process of Facilitation in West Africa, observations point towards the process of Limitation in certain areas, in which case vector control is recommended. Studies on <it>Anopheles</it> species in West Africa have also shown genetic differentiation, cryptic taxa and speciation, insecticide resistance and the existence of molecular and chromosomal forms, all of which could influence the vectorial capacity of the mosquitoes and ultimately the elimination goal. This paper outlines the uniqueness of LF vectors in West Africa and the challenges it poses to the 2020 elimination goal, based on the current MDA strategies.</p>http://www.parasitesandvectors.com/content/5/1/259Lymphatic FilariasisAnopheles vectorsVector-Parasite interactionsWest Africa |
| spellingShingle | de Souza Dziedzom K Koudou Benjamin Kelly-Hope Louise A Wilson Michael D Bockarie Moses J Boakye Daniel A Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis Parasites & Vectors Lymphatic Filariasis Anopheles vectors Vector-Parasite interactions West Africa |
| title | Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis |
| title_full | Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis |
| title_fullStr | Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis |
| title_full_unstemmed | Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis |
| title_short | Diversity and transmission competence in lymphatic filariasis vectors in West Africa, and the implications for accelerated elimination of <it>Anopheles</it>-transmitted filariasis |
| title_sort | diversity and transmission competence in lymphatic filariasis vectors in west africa and the implications for accelerated elimination of it anopheles it transmitted filariasis |
| topic | Lymphatic Filariasis Anopheles vectors Vector-Parasite interactions West Africa |
| url | http://www.parasitesandvectors.com/content/5/1/259 |
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