Ethanol-Induced Alterations in Placental and Fetal Cerebrocortical Annexin-A4 and Cerebral Cavernous Malformation Protein 3 Are Associated With Reductions in Fetal Cortical VEGF Receptor Binding and Microvascular Density

Ethanol-Induced Alterations in Placental and Fetal Cerebrocortical Annexin-A4 and Cerebral Cavernous Malformation Protein 3 Are Associated With Reductions in Fetal Cortical VEGF Receptor Binding and Microvascular Density

Jegou et al. (2012) have reported prenatal alcohol exposure (PAE)-induced reductions of angiogenesis-related proteins in mouse placenta. These effects were associated with striking alterations in microvascular development in neonatal cerebral cortex. Here, we employed a rat model of moderate PAE to...

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Bibliographic Details
Main Authors: Daniel D. Savage, Martina J. Rosenberg, Laurent Coquet, Morgan W. Porch, Nyika A. Allen, Christian Roux, Caroline Aligny, Thierry Jouenne, Bruno J. Gonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
ethanol
placenta
cerebral cortex
cerebral cavernous malformation protein 3
annexin-A4
fetal alcohol spectrum disorder
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00519/full

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