Chronic Kidney Disease Is Associated With Increased Cardiac Corin Expression But Decreased Proatrial Natriuretic Peptide Conversion Activity

Chronic Kidney Disease Is Associated With Increased Cardiac Corin Expression But Decreased Proatrial Natriuretic Peptide Conversion Activity

Background Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease. Corin converts proatrial natriuretic peptide into its active form after being activated by PCSK6 (proprotein convertase subtilisin/kexin type 6) protease. It remains unknown whether the PCSK6/cori...

Full description

Bibliographic Details
Main Authors: Shang‐Feng Yang, Szu‐Yuan Li, Feng‐Yen Lin, Tsung‐Han Hsieh, Po‐Hsun Huang, Shing‐Jong Lin
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atrial natriuretic peptide
chronic kidney disease
corin
PCSK6
uremic cardiomyopathy
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.025208

Similar Items

Similar Items