A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective

Abstract Pancreatic neuroendocrine tumors (PanNETs) are a rare tumor entity with largely unpredictable progression and increasing incidence in developed countries. Molecular pathways involved in PanNETs development are still not elucidated, and specific biomarkers are missing. Moreover, the heteroge...

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Bibliographic Details
Main Authors: Silke D. Werle, Nensi Ikonomi, Ludwig Lausser, Annika M. T. U. Kestler, Felix M. Weidner, Julian D. Schwab, Julia Maier, Malte Buchholz, Thomas M. Gress, Angelika M. R. Kestler, Hans A. Kestler
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-023-00283-8