Hydroxytyrosol (HT) Analogs Act as Potent Antifungals by Direct Disruption of the Fungal Cell Membrane

Hydroxytyrosol (HT) Analogs Act as Potent Antifungals by Direct Disruption of the Fungal Cell Membrane

Fungal infections constitute an emerging threat and a prevalent health problem due to increasing number of immunocompromised people and pharmacological or other treatments aiming at viral infections, cancer or allergies. Currently used antifungals suffer from inefficiency, toxic side effects and dev...

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Bibliographic Details
Main Authors: George Diallinas, Nausica Rafailidou, Ioanna Kalpaktsi, Aikaterini Christina Komianou, Vivian Tsouvali, Iliana Zantza, Emmanuel Mikros, Alexios Leandros Skaltsounis, Ioannis K. Kostakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
fungal pathogens
Aspergillus nidulans
plasma membrane
antimicrobial
resistance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02624/full

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