Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome
Background and Objectives: Irritable bowel syndrome is one of the most common functional gastrointestinal disorders with the prevalence of 10-20% of the world’s population. This syndrome usually manifests as abdominal pain or discomfort associated with altered bowel habits, and it is usually diagnos...
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| Format: | Article |
| Language: | fas |
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Qom University of Medical Sciences
2014-01-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| Subjects: | |
| Online Access: | http://journal.muq.ac.ir/article-1-462-en.html |
| _version_ | 1818657686136291328 |
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| author | Mohammad Reza Ghadir Amir Hossein Ghanooni |
| author_facet | Mohammad Reza Ghadir Amir Hossein Ghanooni |
| author_sort | Mohammad Reza Ghadir |
| collection | DOAJ |
| description | Background and Objectives: Irritable bowel syndrome is one of the most common functional gastrointestinal disorders with the prevalence of 10-20% of the world’s population. This syndrome usually manifests as abdominal pain or discomfort associated with altered bowel habits, and it is usually diagnosed based on patient’s history and there is no specific diagnostic test for it. However, it should be noted that definitive diagnosis is made after ruling out other organic diseases. The most common clinical manifestations are abdominal pain or discomfort, constipation, diarra or alternating constipation and diarrhea, and abdominal bloating. Various mechanisms have been described for pathogenesis of this disorder, including motor dysfunction, visceral hypersensitivity, mild inflammation, and stress. Genetic factors seem to be involved in inflammation and regional immune responses and subsequently, susceptibility to IBS. But it seems that several factors are involved in the presentation of IBS symptoms. Although most patients do not refer for medical care, the disease imposes a considerable cost on patient and healthcare system and considerably overshadows the subject’s quality of life. Having knowledge about the precise pathophysiology and diagnostic criteria are necessary for better identification of patients and choosing a more appropriate treatment approach |
| first_indexed | 2024-12-17T03:45:25Z |
| format | Article |
| id | doaj.art-4cd62a916139470994b58239ab3bc9ea |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-17T03:45:25Z |
| publishDate | 2014-01-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-4cd62a916139470994b58239ab3bc9ea2022-12-21T22:04:55ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752014-01-01766270Review of Pathophysiology and Diagnosis of Irritable Bowel SyndromeMohammad Reza Ghadir0Amir Hossein Ghanooni1 Qom University of Medical Sciences Tehran University of Medical Sciences Background and Objectives: Irritable bowel syndrome is one of the most common functional gastrointestinal disorders with the prevalence of 10-20% of the world’s population. This syndrome usually manifests as abdominal pain or discomfort associated with altered bowel habits, and it is usually diagnosed based on patient’s history and there is no specific diagnostic test for it. However, it should be noted that definitive diagnosis is made after ruling out other organic diseases. The most common clinical manifestations are abdominal pain or discomfort, constipation, diarra or alternating constipation and diarrhea, and abdominal bloating. Various mechanisms have been described for pathogenesis of this disorder, including motor dysfunction, visceral hypersensitivity, mild inflammation, and stress. Genetic factors seem to be involved in inflammation and regional immune responses and subsequently, susceptibility to IBS. But it seems that several factors are involved in the presentation of IBS symptoms. Although most patients do not refer for medical care, the disease imposes a considerable cost on patient and healthcare system and considerably overshadows the subject’s quality of life. Having knowledge about the precise pathophysiology and diagnostic criteria are necessary for better identification of patients and choosing a more appropriate treatment approachhttp://journal.muq.ac.ir/article-1-462-en.htmlirritable bowel syndrome (ibs)abdominal paindiarrheaconstipation |
| spellingShingle | Mohammad Reza Ghadir Amir Hossein Ghanooni Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum irritable bowel syndrome (ibs) abdominal pain diarrhea constipation |
| title | Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome |
| title_full | Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome |
| title_fullStr | Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome |
| title_full_unstemmed | Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome |
| title_short | Review of Pathophysiology and Diagnosis of Irritable Bowel Syndrome |
| title_sort | review of pathophysiology and diagnosis of irritable bowel syndrome |
| topic | irritable bowel syndrome (ibs) abdominal pain diarrhea constipation |
| url | http://journal.muq.ac.ir/article-1-462-en.html |
| work_keys_str_mv | AT mohammadrezaghadir reviewofpathophysiologyanddiagnosisofirritablebowelsyndrome AT amirhosseinghanooni reviewofpathophysiologyanddiagnosisofirritablebowelsyndrome |