Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients
Asymptomatic mouth floor enlargements may be observed in edentulous patients. These masses, which protrude from the mouth floor, may complicate the fitting of dentures and require surgery. Whether this "entity" may be considered an anatomical variation of the mouth floor or represent speci...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of São Paulo
2013-12-01
|
| Series: | Journal of Applied Oral Science |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600540&lng=en&tlng=en |
| _version_ | 1819176773755076608 |
|---|---|
| author | Josiane Costa Rodrigues de SA Elen de Souza TOLENTINO Luciana Reis AZEVEDO-ALANIS Liogi IWAKI FILHO Vanessa Soares LARA Jose Humberto DAMANTE |
| author_facet | Josiane Costa Rodrigues de SA Elen de Souza TOLENTINO Luciana Reis AZEVEDO-ALANIS Liogi IWAKI FILHO Vanessa Soares LARA Jose Humberto DAMANTE |
| author_sort | Josiane Costa Rodrigues de SA |
| collection | DOAJ |
| description | Asymptomatic mouth floor enlargements may be observed in edentulous patients. These masses, which protrude from the mouth floor, may complicate the fitting of dentures and require surgery. Whether this "entity" may be considered an anatomical variation of the mouth floor or represent specific alterations in the sublingual gland is not known. Objective: The aim of this work is to investigate the morphological and morphometric aspects of the sublingual glands of edentulous patients with mouth floor enlargements and compare the glands of these patients with the sublingual glands of human cadavers. Material and Methods: Microscopic evaluation was performed on human sublingual glands from edentulous patients with mouth floor enlargements (n=20) and edentulous cadavers (n=20). The patients and cadavers were of similar ages. The data were compared using Mann-Whitney U, Fisher's exact and Student's t tests (p<0.05). Results: Acinar atrophy, duct-like structures, mononuclear infiltrates, replacement of parenchyma with fibrous/adipose tissue, mucous extravasation and oncocytosis were similar between the groups (p>0.05). Only the variables "autolysis" and "congested blood vessels" presented statistical difference between groups (p=0.014; p=0.043). The morphometric study revealed that the volume densities of acini, ducts, stroma and adipose tissue were similar between the groups (p>0.05). CONCLUSION: The microscopic characteristics of the sublingual glands in mouth floor enlargements in edentulous patients correspond to characteristics associated with the normal aging process. The glands are not pathological and represent an age-related alteration that occurs with or without the presence of the mouth floor enlargements. |
| first_indexed | 2024-12-22T21:16:06Z |
| format | Article |
| id | doaj.art-4cd834424f66433fb12631da1eacc76c |
| institution | Directory Open Access Journal |
| issn | 1678-7765 |
| language | English |
| last_indexed | 2024-12-22T21:16:06Z |
| publishDate | 2013-12-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-4cd834424f66433fb12631da1eacc76c2022-12-21T18:12:21ZengUniversity of São PauloJournal of Applied Oral Science1678-77652013-12-0121654054610.1590/1679-775720130342S1678-77572013000600540Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patientsJosiane Costa Rodrigues de SAElen de Souza TOLENTINOLuciana Reis AZEVEDO-ALANISLiogi IWAKI FILHOVanessa Soares LARAJose Humberto DAMANTEAsymptomatic mouth floor enlargements may be observed in edentulous patients. These masses, which protrude from the mouth floor, may complicate the fitting of dentures and require surgery. Whether this "entity" may be considered an anatomical variation of the mouth floor or represent specific alterations in the sublingual gland is not known. Objective: The aim of this work is to investigate the morphological and morphometric aspects of the sublingual glands of edentulous patients with mouth floor enlargements and compare the glands of these patients with the sublingual glands of human cadavers. Material and Methods: Microscopic evaluation was performed on human sublingual glands from edentulous patients with mouth floor enlargements (n=20) and edentulous cadavers (n=20). The patients and cadavers were of similar ages. The data were compared using Mann-Whitney U, Fisher's exact and Student's t tests (p<0.05). Results: Acinar atrophy, duct-like structures, mononuclear infiltrates, replacement of parenchyma with fibrous/adipose tissue, mucous extravasation and oncocytosis were similar between the groups (p>0.05). Only the variables "autolysis" and "congested blood vessels" presented statistical difference between groups (p=0.014; p=0.043). The morphometric study revealed that the volume densities of acini, ducts, stroma and adipose tissue were similar between the groups (p>0.05). CONCLUSION: The microscopic characteristics of the sublingual glands in mouth floor enlargements in edentulous patients correspond to characteristics associated with the normal aging process. The glands are not pathological and represent an age-related alteration that occurs with or without the presence of the mouth floor enlargements.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600540&lng=en&tlng=enSalivary glandsSublingual glandMorphologyAnatomy |
| spellingShingle | Josiane Costa Rodrigues de SA Elen de Souza TOLENTINO Luciana Reis AZEVEDO-ALANIS Liogi IWAKI FILHO Vanessa Soares LARA Jose Humberto DAMANTE Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients Journal of Applied Oral Science Salivary glands Sublingual gland Morphology Anatomy |
| title | Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| title_full | Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| title_fullStr | Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| title_full_unstemmed | Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| title_short | Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| title_sort | morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients |
| topic | Salivary glands Sublingual gland Morphology Anatomy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600540&lng=en&tlng=en |
| work_keys_str_mv | AT josianecostarodriguesdesa morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients AT elendesouzatolentino morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients AT lucianareisazevedoalanis morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients AT liogiiwakifilho morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients AT vanessasoareslara morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients AT josehumbertodamante morphologyandmorphometryofthehumansublingualglandsinmouthfloorenlargementsofedentulouspatients |