Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease

Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease

Abstract Alpha-synucleinopathy is postulated to be central to both idiopathic rapid eye movement sleep behaviour disorder (iRBD) and Parkinson’s disease (PD). Growing evidence suggests an association between the diminished clearance of α-synuclein and glymphatic system dysfunction. However, evidence...

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Bibliographic Details
Main Authors: Xiaoli Si, Tao Guo, Zhiyun Wang, Yi Fang, Luyan Gu, Lanxiao Cao, Wenyi Yang, Ting Gao, Zhe Song, Jun Tian, Xinzhen Yin, Xiaojun Guan, Cheng Zhou, Jingjing Wu, Xueqin Bai, Xiaocao Liu, Guohua Zhao, Minming Zhang, Jiali Pu, Baorong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00316-9

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