Development of Second Generation Activity-Based Chemical Probes for Sirtuins
NAD<sup>+</sup> (nicotinamide adenine dinucleotide)-dependent protein deacylases, namely, the sirtuins, are important cell adaptor proteins that alter cell physiology in response to low calorie conditions. They are thought to mediate the beneficial effects of calorie restriction to exten...
Main Authors: | Alyson M. Curry, Elizabeth Barton, Wenjia Kang, Daniel V. Mongeluzi, Yana Cen |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/1/11 |
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