Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin

This research is focused on obtaining antimicrobial hybrid materials consisting of poly(lactide) nonwoven fabrics and using phosphoro-organic compound—fosfomycin—as a coating and modifying agent. Polylactide (PLA) presents biodegradable polymer with multifunctional application, widely engaged in med...

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Main Authors: Marcin H. Kudzin, Zdzisława Mrozińska
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/4/768
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author Marcin H. Kudzin
Zdzisława Mrozińska
author_facet Marcin H. Kudzin
Zdzisława Mrozińska
author_sort Marcin H. Kudzin
collection DOAJ
description This research is focused on obtaining antimicrobial hybrid materials consisting of poly(lactide) nonwoven fabrics and using phosphoro-organic compound—fosfomycin—as a coating and modifying agent. Polylactide (PLA) presents biodegradable polymer with multifunctional application, widely engaged in medical related areas. Fosfomycin as functionalized phosphonates presents antibiotic properties expressed by broad spectrum of antimicrobial properties. The analysis of these biofunctionalized nonwoven fabrics processed by the melt-blown technique, included: scanning electron microscopy (SEM), UV/VIS transmittance, FTIR spectrometry, air permeability. The functionalized nonwovens were tested on microbial activity tests against colonies of gram-positive (<i>Staphylococcus aureus</i>) and gram-negative (<i>Escherichia coli</i>) bacteria.
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spelling doaj.art-4ce1f567905041f29275ce0f5a0dac0a2023-11-19T20:19:20ZengMDPI AGPolymers2073-43602020-04-0112476810.3390/polym12040768Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby FosfomycinMarcin H. Kudzin0Zdzisława Mrozińska1The Lukasiewicz Research Network -Textile Research Institute, Brzezinska 5/15, 92-103 Lodz, PolandThe Lukasiewicz Research Network -Textile Research Institute, Brzezinska 5/15, 92-103 Lodz, PolandThis research is focused on obtaining antimicrobial hybrid materials consisting of poly(lactide) nonwoven fabrics and using phosphoro-organic compound—fosfomycin—as a coating and modifying agent. Polylactide (PLA) presents biodegradable polymer with multifunctional application, widely engaged in medical related areas. Fosfomycin as functionalized phosphonates presents antibiotic properties expressed by broad spectrum of antimicrobial properties. The analysis of these biofunctionalized nonwoven fabrics processed by the melt-blown technique, included: scanning electron microscopy (SEM), UV/VIS transmittance, FTIR spectrometry, air permeability. The functionalized nonwovens were tested on microbial activity tests against colonies of gram-positive (<i>Staphylococcus aureus</i>) and gram-negative (<i>Escherichia coli</i>) bacteria.https://www.mdpi.com/2073-4360/12/4/768poly(lactide) nonwoven fabricfosfomycinphosphomycin disodium saltphosphonomycinantibacterial activitypolymer functionalization
spellingShingle Marcin H. Kudzin
Zdzisława Mrozińska
Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
Polymers
poly(lactide) nonwoven fabric
fosfomycin
phosphomycin disodium salt
phosphonomycin
antibacterial activity
polymer functionalization
title Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
title_full Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
title_fullStr Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
title_full_unstemmed Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
title_short Biofunctionalization of Textile Materials. 2. Antimicrobial Modification of Poly(lactide) (PLA) Nonwoven Fabricsby Fosfomycin
title_sort biofunctionalization of textile materials 2 antimicrobial modification of poly lactide pla nonwoven fabricsby fosfomycin
topic poly(lactide) nonwoven fabric
fosfomycin
phosphomycin disodium salt
phosphonomycin
antibacterial activity
polymer functionalization
url https://www.mdpi.com/2073-4360/12/4/768
work_keys_str_mv AT marcinhkudzin biofunctionalizationoftextilematerials2antimicrobialmodificationofpolylactideplanonwovenfabricsbyfosfomycin
AT zdzisławamrozinska biofunctionalizationoftextilematerials2antimicrobialmodificationofpolylactideplanonwovenfabricsbyfosfomycin