Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
Abstract One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there a...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Nefrologia
2019-03-01
|
| Series: | Brazilian Journal of Nephrology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005012104&lng=en&tlng=en |
| _version_ | 1818827514566410240 |
|---|---|
| author | Sara Fernandes Catarina Teixeira Luis Pedro Falcão Ana Cortesão Costa Mário Raimundo Sónia Silva João Cardoso Edgar De Almeida |
| author_facet | Sara Fernandes Catarina Teixeira Luis Pedro Falcão Ana Cortesão Costa Mário Raimundo Sónia Silva João Cardoso Edgar De Almeida |
| author_sort | Sara Fernandes |
| collection | DOAJ |
| description | Abstract One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed connective tissue disease (MCTD). The authors report a case of ANCA-negative CrGN associated with a MCTD. |
| first_indexed | 2024-12-19T00:44:46Z |
| format | Article |
| id | doaj.art-4ce93c090394447297910305bb9f6091 |
| institution | Directory Open Access Journal |
| issn | 2175-8239 |
| language | English |
| last_indexed | 2024-12-19T00:44:46Z |
| publishDate | 2019-03-01 |
| publisher | Sociedade Brasileira de Nefrologia |
| record_format | Article |
| series | Brazilian Journal of Nephrology |
| spelling | doaj.art-4ce93c090394447297910305bb9f60912022-12-21T20:44:19ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392019-03-01010.1590/2175-8239-jbn-2019-0003S0101-28002019005012104Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case studySara FernandesCatarina TeixeiraLuis Pedro FalcãoAna Cortesão CostaMário RaimundoSónia SilvaJoão CardosoEdgar De AlmeidaAbstract One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed connective tissue disease (MCTD). The authors report a case of ANCA-negative CrGN associated with a MCTD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005012104&lng=en&tlng=enGlomerulonefriteDoença Mista do Tecido Conjuntivo. |
| spellingShingle | Sara Fernandes Catarina Teixeira Luis Pedro Falcão Ana Cortesão Costa Mário Raimundo Sónia Silva João Cardoso Edgar De Almeida Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study Brazilian Journal of Nephrology Glomerulonefrite Doença Mista do Tecido Conjuntivo. |
| title | Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study |
| title_full | Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study |
| title_fullStr | Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study |
| title_full_unstemmed | Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study |
| title_short | Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study |
| title_sort | anca negative pauci immune crescentic glomerulonephritis and mixed connective tissue disease a case study |
| topic | Glomerulonefrite Doença Mista do Tecido Conjuntivo. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005012104&lng=en&tlng=en |
| work_keys_str_mv | AT sarafernandes ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT catarinateixeira ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT luispedrofalcao ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT anacortesaocosta ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT marioraimundo ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT soniasilva ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT joaocardoso ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy AT edgardealmeida ancanegativepauciimmunecrescenticglomerulonephritisandmixedconnectivetissuediseaseacasestudy |