Developmental nonlinearity drives phenotypic robustness
Developmental processes often involve nonlinearities, but the consequences for translating genotype to phenotype are not well characterized. Here, Green et al. vary Fgf8 signaling across allelic series of mice and show that phenotypic robustness in craniofacial shape is explained by a nonlinear effe...
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Bibliographic Details
| Main Authors: |
Rebecca M. Green,
Jennifer L. Fish,
Nathan M. Young,
Francis J. Smith,
Benjamin Roberts,
Katie Dolan,
Irene Choi,
Courtney L. Leach,
Paul Gordon,
James M. Cheverud,
Charles C. Roseman,
Trevor J. Williams,
Ralph S. Marcucio,
Benedikt Hallgrímsson |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2017-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-017-02037-7
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