Mutations in Coding and Non-Coding Regions in Varicella-Zoster Virus Causing Fatal Hemorrhagic Fever Without Rash in an Immunocompetent Patient: Case Report

Mutations in Coding and Non-Coding Regions in Varicella-Zoster Virus Causing Fatal Hemorrhagic Fever Without Rash in an Immunocompetent Patient: Case Report

Abstract Introduction We report the case of a fatal hemorrhagic varicella primary infection in an immunocompetent man and whole-genome characterization of the virus for the investigation of biomarkers of virulence. Case A 38-year-old patient born in Nigeria presented to the emergency department with...

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Bibliographic Details
Main Authors: Juan Camacho, Anabel Negredo, Bartolomé Carrilero, Manuel Segovia, Antonio Moreno, Francisco Pozo, Juan-Emilio Echevarría, José-Manuel Echevarría, M. Paz Sánchez-Seco, David Tarragó
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-10-01
Series:Infectious Diseases and Therapy
Subjects:
Hemorrhagic fever
Varicella-zoster virus
Metagenomic whole genome sequencing (mWGS)
Varicella-zoster virus clades
Varicella-zoster virus virulence
Varicella-zoster virus mutations
Online Access:https://doi.org/10.1007/s40121-023-00884-0

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