Chronic gastritis may predict risk of cerebral small vessel disease
Abstract Background and purpose Chronic gastritis, especially that caused by helicobacter pylori (HP) infection, has been associated with increased risk of ischemic stroke. But the relationship between chronic gastritis and cerebral small vessel disease (CSVD) remains largely undetermined. This stud...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-023-03009-6 |
| _version_ | 1797397942947020800 |
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| author | Cunsheng Wei Chang Tan Xuemei Zhang Xin Shen Zongliang Xu Junrong Li Gelin Xu |
| author_facet | Cunsheng Wei Chang Tan Xuemei Zhang Xin Shen Zongliang Xu Junrong Li Gelin Xu |
| author_sort | Cunsheng Wei |
| collection | DOAJ |
| description | Abstract Background and purpose Chronic gastritis, especially that caused by helicobacter pylori (HP) infection, has been associated with increased risk of ischemic stroke. But the relationship between chronic gastritis and cerebral small vessel disease (CSVD) remains largely undetermined. This study aimed to determine the potential predictors for CSVD, with chronic gastritis and its proxies as alternatives. Method Patients aged 18 years or older with indications for electronic gastroscopy were enrolled. Presence of CSVD was evaluated with brain magnetic resonance imaging (MRI) results. Degree of CSVD was scored according to established criteria. Logistic regression analysis was used for identifying possible risk factors for CSVD. Results Of the 1191 enrolled patients, 757 (63.6%) were identified as with, and 434 (36.4%) as without CSVD. Multivariate analysis indicated that patients with chronic atrophic gastritis had an increased risk for CSVD than those without (adjusted odds ratio = 1.58; 95% CI, 1.08–2.32; P < 0.05). Conclusions Chronic atrophic gastritis is associated with the presence of CSVD. We should routinely screen the presence of CSVD for patients with chronic atrophic gastritis. |
| first_indexed | 2024-03-09T01:17:29Z |
| format | Article |
| id | doaj.art-4ceee0c0d6b44f99ae56973a8a4bf7df |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-03-09T01:17:29Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-4ceee0c0d6b44f99ae56973a8a4bf7df2023-12-10T12:21:03ZengBMCBMC Gastroenterology1471-230X2023-12-012311610.1186/s12876-023-03009-6Chronic gastritis may predict risk of cerebral small vessel diseaseCunsheng Wei0Chang Tan1Xuemei Zhang2Xin Shen3Zongliang Xu4Junrong Li5Gelin Xu6Department of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Affiliated Jiangning Hospital With Nanjing Medical UniversityDepartment of Neurology, Jinling Hospital, Medical School of Nanjing UniversityAbstract Background and purpose Chronic gastritis, especially that caused by helicobacter pylori (HP) infection, has been associated with increased risk of ischemic stroke. But the relationship between chronic gastritis and cerebral small vessel disease (CSVD) remains largely undetermined. This study aimed to determine the potential predictors for CSVD, with chronic gastritis and its proxies as alternatives. Method Patients aged 18 years or older with indications for electronic gastroscopy were enrolled. Presence of CSVD was evaluated with brain magnetic resonance imaging (MRI) results. Degree of CSVD was scored according to established criteria. Logistic regression analysis was used for identifying possible risk factors for CSVD. Results Of the 1191 enrolled patients, 757 (63.6%) were identified as with, and 434 (36.4%) as without CSVD. Multivariate analysis indicated that patients with chronic atrophic gastritis had an increased risk for CSVD than those without (adjusted odds ratio = 1.58; 95% CI, 1.08–2.32; P < 0.05). Conclusions Chronic atrophic gastritis is associated with the presence of CSVD. We should routinely screen the presence of CSVD for patients with chronic atrophic gastritis.https://doi.org/10.1186/s12876-023-03009-6Cerebral small vessel diseaseChronic atrophic gastritisInflammationStrokeRisk |
| spellingShingle | Cunsheng Wei Chang Tan Xuemei Zhang Xin Shen Zongliang Xu Junrong Li Gelin Xu Chronic gastritis may predict risk of cerebral small vessel disease BMC Gastroenterology Cerebral small vessel disease Chronic atrophic gastritis Inflammation Stroke Risk |
| title | Chronic gastritis may predict risk of cerebral small vessel disease |
| title_full | Chronic gastritis may predict risk of cerebral small vessel disease |
| title_fullStr | Chronic gastritis may predict risk of cerebral small vessel disease |
| title_full_unstemmed | Chronic gastritis may predict risk of cerebral small vessel disease |
| title_short | Chronic gastritis may predict risk of cerebral small vessel disease |
| title_sort | chronic gastritis may predict risk of cerebral small vessel disease |
| topic | Cerebral small vessel disease Chronic atrophic gastritis Inflammation Stroke Risk |
| url | https://doi.org/10.1186/s12876-023-03009-6 |
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