Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction
Background: The role of left ventricular (LV) mechanical dispersion estimated after an ST elevation acute myocardial infarction (STEMI) remains unclear. Methods: The study participants were 208 consecutive patients (152 men, age = 72 years) presenting with STEMI for the first time who underwent prim...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | International Journal of Cardiology: Heart & Vasculature |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S235290672200077X |
| _version_ | 1818213971851739136 |
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| author | Noriaki Iwahashi Jin Kirigaya Masaomi Gohbara Takeru Abe Mutsuo Horii Yohei Hanajima Noriko Toya Hironori Takahashi Hidekuni Kirigaya Yugo Minamimoto Yuichiro Kimura Kozo Okada Yasushi Matsuzawa Kiyoshi Hibi Masami Kosuge Toshiaki Ebina Kouichi Tamura Kazuo Kimura |
| author_facet | Noriaki Iwahashi Jin Kirigaya Masaomi Gohbara Takeru Abe Mutsuo Horii Yohei Hanajima Noriko Toya Hironori Takahashi Hidekuni Kirigaya Yugo Minamimoto Yuichiro Kimura Kozo Okada Yasushi Matsuzawa Kiyoshi Hibi Masami Kosuge Toshiaki Ebina Kouichi Tamura Kazuo Kimura |
| author_sort | Noriaki Iwahashi |
| collection | DOAJ |
| description | Background: The role of left ventricular (LV) mechanical dispersion estimated after an ST elevation acute myocardial infarction (STEMI) remains unclear. Methods: The study participants were 208 consecutive patients (152 men, age = 72 years) presenting with STEMI for the first time who underwent primary percutaneous coronary intervention (PCI) within 12 h of STEMI onset. Within 48 h of PCI (mean = 24 h), 2D and 3D speckle-tracking echocardiography were performed. The global longitudinal strain (GLS) was calculated using 3D (3D-GLS) and 2D (2D-GLS) speckle tracking. Mechanical dispersion was defined using the standard deviation (SD) of the time to regional peak longitudinal strain (LS) for all 16 segments for both 2D-STE and 3D-STE (2D-LS-SD, 3D-LS-SD). Infarct size was estimated by Tc99m-sestamibi as the total area of < 50% of the uptake area at 2 weeks. The patients were followed up for a longer period of time (median118months) and checked for major adverse cardiac events (MACE: cardiac death, heart failure). Results: During follow-up, 55 patients experienced MACE. The cut-off values were determined using receiver operating characteristic curves. The multivariate analysis revealed that a 3D-LS-SD > 56.7 ms was a significant predictor of MACEs (hazard ratio = 1.991, 95% confidence interval 1.033–3.613, p = 0.03), but 2D-LS-SD > 58.1 ms was not an independent predictor of MACEs (hazard ratio = 1.577, 95% confidence interval 0.815–3.042, p = 0.1). Furthermore, the combination of 3D-GLS and 3D-LS-SD had accurate predictability for MACE, as shown by the Kaplan-Meier curves (log rank, χ2 = 94.1, p < 0.0001). Conclusions: LV mechanical dispersion besides 3D-GLS assessed by 3D-STE immediately after PCI can predict long-term prognosis. |
| first_indexed | 2024-12-12T06:12:46Z |
| format | Article |
| id | doaj.art-4cefa998b30b405ca6384ee8d3a1b956 |
| institution | Directory Open Access Journal |
| issn | 2352-9067 |
| language | English |
| last_indexed | 2024-12-12T06:12:46Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology: Heart & Vasculature |
| spelling | doaj.art-4cefa998b30b405ca6384ee8d3a1b9562022-12-22T00:35:08ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672022-06-0140101028Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarctionNoriaki Iwahashi0Jin Kirigaya1Masaomi Gohbara2Takeru Abe3Mutsuo Horii4Yohei Hanajima5Noriko Toya6Hironori Takahashi7Hidekuni Kirigaya8Yugo Minamimoto9Yuichiro Kimura10Kozo Okada11Yasushi Matsuzawa12Kiyoshi Hibi13Masami Kosuge14Toshiaki Ebina15Kouichi Tamura16Kazuo Kimura17Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan; Corresponding author at: Division of Cardiology, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan.Division of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDepartment of Emergency Medicine, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDepartment of Radiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, JapanDivision of Cardiology, Yokohama City University Medical Center, Yokohama, JapanBackground: The role of left ventricular (LV) mechanical dispersion estimated after an ST elevation acute myocardial infarction (STEMI) remains unclear. Methods: The study participants were 208 consecutive patients (152 men, age = 72 years) presenting with STEMI for the first time who underwent primary percutaneous coronary intervention (PCI) within 12 h of STEMI onset. Within 48 h of PCI (mean = 24 h), 2D and 3D speckle-tracking echocardiography were performed. The global longitudinal strain (GLS) was calculated using 3D (3D-GLS) and 2D (2D-GLS) speckle tracking. Mechanical dispersion was defined using the standard deviation (SD) of the time to regional peak longitudinal strain (LS) for all 16 segments for both 2D-STE and 3D-STE (2D-LS-SD, 3D-LS-SD). Infarct size was estimated by Tc99m-sestamibi as the total area of < 50% of the uptake area at 2 weeks. The patients were followed up for a longer period of time (median118months) and checked for major adverse cardiac events (MACE: cardiac death, heart failure). Results: During follow-up, 55 patients experienced MACE. The cut-off values were determined using receiver operating characteristic curves. The multivariate analysis revealed that a 3D-LS-SD > 56.7 ms was a significant predictor of MACEs (hazard ratio = 1.991, 95% confidence interval 1.033–3.613, p = 0.03), but 2D-LS-SD > 58.1 ms was not an independent predictor of MACEs (hazard ratio = 1.577, 95% confidence interval 0.815–3.042, p = 0.1). Furthermore, the combination of 3D-GLS and 3D-LS-SD had accurate predictability for MACE, as shown by the Kaplan-Meier curves (log rank, χ2 = 94.1, p < 0.0001). Conclusions: LV mechanical dispersion besides 3D-GLS assessed by 3D-STE immediately after PCI can predict long-term prognosis.http://www.sciencedirect.com/science/article/pii/S235290672200077XSTEMISpeckle trackingThree dimensional echocardiographyMechanical dispersionPrognosis |
| spellingShingle | Noriaki Iwahashi Jin Kirigaya Masaomi Gohbara Takeru Abe Mutsuo Horii Yohei Hanajima Noriko Toya Hironori Takahashi Hidekuni Kirigaya Yugo Minamimoto Yuichiro Kimura Kozo Okada Yasushi Matsuzawa Kiyoshi Hibi Masami Kosuge Toshiaki Ebina Kouichi Tamura Kazuo Kimura Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction International Journal of Cardiology: Heart & Vasculature STEMI Speckle tracking Three dimensional echocardiography Mechanical dispersion Prognosis |
| title | Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction |
| title_full | Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction |
| title_fullStr | Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction |
| title_full_unstemmed | Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction |
| title_short | Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction |
| title_sort | mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with st elevation myocardial infarction |
| topic | STEMI Speckle tracking Three dimensional echocardiography Mechanical dispersion Prognosis |
| url | http://www.sciencedirect.com/science/article/pii/S235290672200077X |
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