Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand
Adequate nutritional status may influence progression to frailty. The purpose of this study is to determine the prevalence of frailty and examine the relationship between dietary protein intake and the transition between frailty states and mortality in advanced age. We used data from a longitudinal...
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MDPI AG
2021-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/8/2843 |
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| author | Ruth Teh Nuno Mendonça Marama Muru-Lanning Sue MacDonell Louise Robinson Ngaire Kerse |
| author_facet | Ruth Teh Nuno Mendonça Marama Muru-Lanning Sue MacDonell Louise Robinson Ngaire Kerse |
| author_sort | Ruth Teh |
| collection | DOAJ |
| description | Adequate nutritional status may influence progression to frailty. The purpose of this study is to determine the prevalence of frailty and examine the relationship between dietary protein intake and the transition between frailty states and mortality in advanced age. We used data from a longitudinal cohort study of Māori (80–90 years) and non-Māori (85 years). Dietary assessments (24-h multiple pass dietary recalls) were completed at the second year of follow-up (wave 2 and forms the baseline in this study). Frailty was defined using the Fried Frailty criteria. Multi-state modelling examined the association of protein intake and transitions between frailty states and death over four years. Over three quarters of participants were pre-frail or frail at baseline (62% and 16%, respectively). Those who were frail had a higher co-morbidity (<i>p</i> < 0.05), where frailty state changed, 44% showed a worsening of frailty status (robust → pre-frail or pre-frail → frail). Those with higher protein intake (g/kg body weight/day) were less likely to transition from robust to pre-frail [Hazard Ratio (95% Confidence Interval): 0.28 (0.08–0.91)] but also from pre-frail to robust [0.24 (0.06–0.93)]. Increased protein intake was associated with lower risk of transitioning from pre-frailty to death [0.19 (0.04–0.80)], and this association was moderated by energy intake [0.22 (0.03–1.71)]. Higher protein intake in this sample of octogenarians was associated with both better and worse outcomes. |
| first_indexed | 2024-03-10T08:30:08Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T08:30:08Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-4cf229256eef40d580c1ebbb29b0ef9f2023-11-22T09:06:58ZengMDPI AGNutrients2072-66432021-08-01138284310.3390/nu13082843Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New ZealandRuth Teh0Nuno Mendonça1Marama Muru-Lanning2Sue MacDonell3Louise Robinson4Ngaire Kerse5Department of General Practice and Primary Care, University of Auckland, Auckland 1142, New ZealandEpiDoC Unit, CEDOC, NOVA Medical School, Universidade Nova de Lisboa (UNL), 1099-085 Lisbon, PortugalJames Henare Māori Research Centre, University of Auckland, Auckland 1142, New ZealandDepartment of General Practice and Primary Care, University of Auckland, Auckland 1142, New ZealandPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE1 7RU, UKDepartment of General Practice and Primary Care, University of Auckland, Auckland 1142, New ZealandAdequate nutritional status may influence progression to frailty. The purpose of this study is to determine the prevalence of frailty and examine the relationship between dietary protein intake and the transition between frailty states and mortality in advanced age. We used data from a longitudinal cohort study of Māori (80–90 years) and non-Māori (85 years). Dietary assessments (24-h multiple pass dietary recalls) were completed at the second year of follow-up (wave 2 and forms the baseline in this study). Frailty was defined using the Fried Frailty criteria. Multi-state modelling examined the association of protein intake and transitions between frailty states and death over four years. Over three quarters of participants were pre-frail or frail at baseline (62% and 16%, respectively). Those who were frail had a higher co-morbidity (<i>p</i> < 0.05), where frailty state changed, 44% showed a worsening of frailty status (robust → pre-frail or pre-frail → frail). Those with higher protein intake (g/kg body weight/day) were less likely to transition from robust to pre-frail [Hazard Ratio (95% Confidence Interval): 0.28 (0.08–0.91)] but also from pre-frail to robust [0.24 (0.06–0.93)]. Increased protein intake was associated with lower risk of transitioning from pre-frailty to death [0.19 (0.04–0.80)], and this association was moderated by energy intake [0.22 (0.03–1.71)]. Higher protein intake in this sample of octogenarians was associated with both better and worse outcomes.https://www.mdpi.com/2072-6643/13/8/2843frailtymortalityprotein deficiencyindigenous healthmulti-state modelling |
| spellingShingle | Ruth Teh Nuno Mendonça Marama Muru-Lanning Sue MacDonell Louise Robinson Ngaire Kerse Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand Nutrients frailty mortality protein deficiency indigenous health multi-state modelling |
| title | Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand |
| title_full | Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand |
| title_fullStr | Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand |
| title_full_unstemmed | Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand |
| title_short | Dietary Protein Intake and Transition between Frailty States in Octogenarians Living in New Zealand |
| title_sort | dietary protein intake and transition between frailty states in octogenarians living in new zealand |
| topic | frailty mortality protein deficiency indigenous health multi-state modelling |
| url | https://www.mdpi.com/2072-6643/13/8/2843 |
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