Effects of iron homeostasis on epigenetic age acceleration: a two-sample Mendelian randomization study

Effects of iron homeostasis on epigenetic age acceleration: a two-sample Mendelian randomization study

Abstract Background Epigenetic clocks constructed from DNA methylation patterns have emerged as excellent predictors of aging and aging-related health outcomes. Iron, a crucial element, is meticulously regulated within organisms, a phenomenon referred as iron homeostasis. Previous researches have de...

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Bibliographic Details
Main Authors: Zhihao Wang, Yi Liu, Shuxin Zhang, Yunbo Yuan, Siliang Chen, Wenhao Li, Mingrong Zuo, Yufan Xiang, Tengfei Li, Wanchun Yang, Yuan Yang, Yanhui Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Clinical Epigenetics
Subjects:
Iron metabolism
Iron homeostasis
Senescence
Aging
Epigenetic age acceleration
Mendelian randomization
Online Access:https://doi.org/10.1186/s13148-023-01575-w

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