Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer

Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer

Tumor-associated macrophages (TAMs) promote progression of breast cancer and other solid malignancies via immunosuppressive, pro-angiogenic and pro-metastatic effects. Tumor-promoting TAMs tend to express M2-like macrophage markers, including CD163. Histopathological assessments suggest that the den...

Full description

Bibliographic Details
Main Authors: Brenton A. Maisel, Misung Yi, Amy R. Peck, Yunguang Sun, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, Hai Hu, Marja T. Nevalainen, Takemi Tanaka, Nicole Simone, Li Lily Wang, Hallgeir Rui, Inna Chervoneva
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
tumor-associated macrophages
cancer biomarkers
tumor immune microenvironment
spatially-resolved immunohistochemistry data
marked point patterns
nearest neighbor distance
Online Access:https://www.mdpi.com/2072-6694/14/2/308

Internet

https://www.mdpi.com/2072-6694/14/2/308

Similar Items