Spatholobus suberectus inhibits lipogenesis and tumorigenesis in triple-negative breast cancer via activation of AMPK-ACC and K-Ras-ERK signaling pathway

Spatholobus suberectus inhibits lipogenesis and tumorigenesis in triple-negative breast cancer via activation of AMPK-ACC and K-Ras-ERK signaling pathway

Background and aim: Triple-negative breast cancer (TNBC) is a highly invasive type of breast cancer with a poor prognosis. Currently, there are no effective management strategies for TNBC. Earlier, our lab reported the percolation of Spatholobus suberectus for the treatment of breast cancer. Lipid m...

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Bibliographic Details
Main Authors: Xiaohui Zeng, Guowei Gong, Kumar Ganesan, Yi Wen, Qingqing Liu, Juncheng Zhuo, Jianming Wu, Jianping Chen
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Spatholobi suberectus
Lipogenesis
TNBC
Therapy
Natural product
Proteomic and metabolomic analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411023000998

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