Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers
Abstract MRI plays important roles in endometrial and cervical cancer assessment, from detection to recurrent disease evaluation. Endometrial cancer (EC) is the most common malignant tumor of the female genital tract in Western countries. EC patients are divided into risk categories based on histopa...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-02-01
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| Series: | Insights into Imaging |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13244-019-0696-8 |
| _version_ | 1818338235332427776 |
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| author | María Milagros Otero-García Alicia Mesa-Álvarez Olivera Nikolic Patricia Blanco-Lobato Marijana Basta-Nikolic Rafael Menéndez de Llano-Ortega Laura Paredes-Velázquez Nikola Nikolic Magda Szewczyk-Bieda |
| author_facet | María Milagros Otero-García Alicia Mesa-Álvarez Olivera Nikolic Patricia Blanco-Lobato Marijana Basta-Nikolic Rafael Menéndez de Llano-Ortega Laura Paredes-Velázquez Nikola Nikolic Magda Szewczyk-Bieda |
| author_sort | María Milagros Otero-García |
| collection | DOAJ |
| description | Abstract MRI plays important roles in endometrial and cervical cancer assessment, from detection to recurrent disease evaluation. Endometrial cancer (EC) is the most common malignant tumor of the female genital tract in Western countries. EC patients are divided into risk categories based on histopathological tumor type, grade, and myometrial invasion depth. EC is surgically staged using the International Federation of Gynecology and Obstetrics (FIGO) system. Since FIGO (2009) stage correlates with prognosis, preoperative staging is essential for tailored treatment. MRI reveals myometrial invasion depth, which correlates with tumor grade and lymph node metastases, and thus correlates with prognosis. Cervical cancer (CC) is the second most common cancer, and the third leading cause of cancer-related death among females in developing countries. The FIGO Gynecologic Oncology Committee recently revised its CC staging guidelines, allowing staging based on imaging and pathological findings when available. The revised FIGO (2018) staging includes node involvement and thus enables both therapy selection and evaluation, prognosis estimation, and calculation of end results. MRI can accurately assess prognostic indicators, e.g., tumor size, parametrial invasion, pelvic sidewall, and lymph node invasion. Despite these important roles of MRI, radiologists still face challenges due to the technical and interpretation pitfalls of MRI during all phases of endometrial and cervical cancer evaluation. Awareness of mimics that can simulate both cancers is critical. With careful application, functional MRI with DWI and DCE sequences can help establish a correct diagnosis, although it is sometimes necessary to perform biopsy and histopathological analysis. |
| first_indexed | 2024-12-13T15:07:53Z |
| format | Article |
| id | doaj.art-4cf5fb653a924d2cbd08b5e8f3289340 |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-12-13T15:07:53Z |
| publishDate | 2019-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-4cf5fb653a924d2cbd08b5e8f32893402022-12-21T23:40:57ZengSpringerOpenInsights into Imaging1869-41012019-02-0110112210.1186/s13244-019-0696-8Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickersMaría Milagros Otero-García0Alicia Mesa-Álvarez1Olivera Nikolic2Patricia Blanco-Lobato3Marijana Basta-Nikolic4Rafael Menéndez de Llano-Ortega5Laura Paredes-Velázquez6Nikola Nikolic7Magda Szewczyk-Bieda8Department of Radiology, Hospital Universitario de VigoDepartment of Radiology, Hospital Universitario Central de AsturiasClinical Centre of Vojvodina, Centre of Radiology, Faculty of Medicine, University of Novi SadDepartment of Radiology, Hospital Universitario de VigoClinical Centre of Vojvodina, Centre of Radiology, Faculty of Medicine, University of Novi SadDepartment of Radiology, Hospital Universitario Central de AsturiasDepartment of Radiology, Hospital Universitario de VigoCentre of Radiology, Clinical Centre of VojvodinaDepartment of Clinical Radiology, Ninewells Hospital and Medical SchoolAbstract MRI plays important roles in endometrial and cervical cancer assessment, from detection to recurrent disease evaluation. Endometrial cancer (EC) is the most common malignant tumor of the female genital tract in Western countries. EC patients are divided into risk categories based on histopathological tumor type, grade, and myometrial invasion depth. EC is surgically staged using the International Federation of Gynecology and Obstetrics (FIGO) system. Since FIGO (2009) stage correlates with prognosis, preoperative staging is essential for tailored treatment. MRI reveals myometrial invasion depth, which correlates with tumor grade and lymph node metastases, and thus correlates with prognosis. Cervical cancer (CC) is the second most common cancer, and the third leading cause of cancer-related death among females in developing countries. The FIGO Gynecologic Oncology Committee recently revised its CC staging guidelines, allowing staging based on imaging and pathological findings when available. The revised FIGO (2018) staging includes node involvement and thus enables both therapy selection and evaluation, prognosis estimation, and calculation of end results. MRI can accurately assess prognostic indicators, e.g., tumor size, parametrial invasion, pelvic sidewall, and lymph node invasion. Despite these important roles of MRI, radiologists still face challenges due to the technical and interpretation pitfalls of MRI during all phases of endometrial and cervical cancer evaluation. Awareness of mimics that can simulate both cancers is critical. With careful application, functional MRI with DWI and DCE sequences can help establish a correct diagnosis, although it is sometimes necessary to perform biopsy and histopathological analysis.http://link.springer.com/article/10.1186/s13244-019-0696-8Endometrial cancerCervical cancerMagnetic resonanceDiffusionLymph nodes |
| spellingShingle | María Milagros Otero-García Alicia Mesa-Álvarez Olivera Nikolic Patricia Blanco-Lobato Marijana Basta-Nikolic Rafael Menéndez de Llano-Ortega Laura Paredes-Velázquez Nikola Nikolic Magda Szewczyk-Bieda Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers Insights into Imaging Endometrial cancer Cervical cancer Magnetic resonance Diffusion Lymph nodes |
| title | Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers |
| title_full | Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers |
| title_fullStr | Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers |
| title_full_unstemmed | Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers |
| title_short | Role of MRI in staging and follow-up of endometrial and cervical cancer: pitfalls and mimickers |
| title_sort | role of mri in staging and follow up of endometrial and cervical cancer pitfalls and mimickers |
| topic | Endometrial cancer Cervical cancer Magnetic resonance Diffusion Lymph nodes |
| url | http://link.springer.com/article/10.1186/s13244-019-0696-8 |
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