Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients
Abstract Background Growing evidence suggests that critical illness often results in significant long-term neurocognitive impairments in one-third of survivors. Although these neurocognitive impairments are long-lasting and devastating for survivors, rehabilitation rarely occurs during or after crit...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2017-08-01
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| Series: | Annals of Intensive Care |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13613-017-0303-4 |
| _version_ | 1811260094046797824 |
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| author | Marc Turon Sol Fernandez-Gonzalo Mercè Jodar Gemma Gomà Jaume Montanya David Hernando Raquel Bailón Candelaria de Haro Victor Gomez-Simon Josefina Lopez-Aguilar Rudys Magrans Melcior Martinez-Perez Joan Carles Oliva Lluís Blanch |
| author_facet | Marc Turon Sol Fernandez-Gonzalo Mercè Jodar Gemma Gomà Jaume Montanya David Hernando Raquel Bailón Candelaria de Haro Victor Gomez-Simon Josefina Lopez-Aguilar Rudys Magrans Melcior Martinez-Perez Joan Carles Oliva Lluís Blanch |
| author_sort | Marc Turon |
| collection | DOAJ |
| description | Abstract Background Growing evidence suggests that critical illness often results in significant long-term neurocognitive impairments in one-third of survivors. Although these neurocognitive impairments are long-lasting and devastating for survivors, rehabilitation rarely occurs during or after critical illness. Our aim is to describe an early neurocognitive stimulation intervention based on virtual reality for patients who are critically ill and to present the results of a proof-of-concept study testing the feasibility, safety, and suitability of this intervention. Methods Twenty critically ill adult patients undergoing or having undergone mechanical ventilation for ≥24 h received daily 20-min neurocognitive stimulation sessions when awake and alert during their ICU stay. The difficulty of the exercises included in the sessions progressively increased over successive sessions. Physiological data were recorded before, during, and after each session. Safety was assessed through heart rate, peripheral oxygen saturation, and respiratory rate. Heart rate variability analysis, an indirect measure of autonomic activity sensitive to cognitive demands, was used to assess the efficacy of the exercises in stimulating attention and working memory. Results Patients successfully completed the sessions on most days. No sessions were stopped early for safety concerns, and no adverse events occurred. Heart rate variability analysis showed that the exercises stimulated attention and working memory. Critically ill patients considered the sessions enjoyable and relaxing without being overly fatiguing. Conclusions The results in this proof-of-concept study suggest that a virtual-reality-based neurocognitive intervention is feasible, safe, and tolerable, stimulating cognitive functions and satisfying critically ill patients. Future studies will evaluate the impact of interventions on neurocognitive outcomes. Trial registration Clinical trials.gov identifier: NCT02078206 |
| first_indexed | 2024-04-12T18:41:21Z |
| format | Article |
| id | doaj.art-4cfa4586835449b88f57347f57f334fa |
| institution | Directory Open Access Journal |
| issn | 2110-5820 |
| language | English |
| last_indexed | 2024-04-12T18:41:21Z |
| publishDate | 2017-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Annals of Intensive Care |
| spelling | doaj.art-4cfa4586835449b88f57347f57f334fa2022-12-22T03:20:45ZengSpringerOpenAnnals of Intensive Care2110-58202017-08-017111110.1186/s13613-017-0303-4Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patientsMarc Turon0Sol Fernandez-Gonzalo1Mercè Jodar2Gemma Gomà3Jaume Montanya4David Hernando5Raquel Bailón6Candelaria de Haro7Victor Gomez-Simon8Josefina Lopez-Aguilar9Rudys Magrans10Melcior Martinez-Perez11Joan Carles Oliva12Lluís Blanch13Centro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIIInstitut d’Investigació i Innovació Parc Taulí (I3PT), Fundació Parc TaulíDepartment of Clinical and Health Psychology, Universitat Autònoma de BarcelonaInstitut d’Investigació i Innovació Parc Taulí (I3PT), Fundació Parc TaulíCentro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIIBSICOS Group, 13A, Universidad de Zaragoza&CIBER-BBNBSICOS Group, 13A, Universidad de Zaragoza&CIBER-BBNCritical Care Department, Parc Taulí Hospital Universitari, Institut d’Investigació i Innovació Parc Taulí (I3PT), Universitat Autònoma de BarcelonaCritical Care Department, Parc Taulí Hospital Universitari, Institut d’Investigació i Innovació Parc Taulí (I3PT), Universitat Autònoma de BarcelonaCentro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIICentro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIICentro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIIInstitut d’Investigació i Innovació Parc Taulí (I3PT), Fundació Parc TaulíCentro de Investigación Biomédica En Red en Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos IIIAbstract Background Growing evidence suggests that critical illness often results in significant long-term neurocognitive impairments in one-third of survivors. Although these neurocognitive impairments are long-lasting and devastating for survivors, rehabilitation rarely occurs during or after critical illness. Our aim is to describe an early neurocognitive stimulation intervention based on virtual reality for patients who are critically ill and to present the results of a proof-of-concept study testing the feasibility, safety, and suitability of this intervention. Methods Twenty critically ill adult patients undergoing or having undergone mechanical ventilation for ≥24 h received daily 20-min neurocognitive stimulation sessions when awake and alert during their ICU stay. The difficulty of the exercises included in the sessions progressively increased over successive sessions. Physiological data were recorded before, during, and after each session. Safety was assessed through heart rate, peripheral oxygen saturation, and respiratory rate. Heart rate variability analysis, an indirect measure of autonomic activity sensitive to cognitive demands, was used to assess the efficacy of the exercises in stimulating attention and working memory. Results Patients successfully completed the sessions on most days. No sessions were stopped early for safety concerns, and no adverse events occurred. Heart rate variability analysis showed that the exercises stimulated attention and working memory. Critically ill patients considered the sessions enjoyable and relaxing without being overly fatiguing. Conclusions The results in this proof-of-concept study suggest that a virtual-reality-based neurocognitive intervention is feasible, safe, and tolerable, stimulating cognitive functions and satisfying critically ill patients. Future studies will evaluate the impact of interventions on neurocognitive outcomes. Trial registration Clinical trials.gov identifier: NCT02078206http://link.springer.com/article/10.1186/s13613-017-0303-4Neurocognitive impairmentsCritically ill patientsNeurocognitive stimulationVirtual realityEarly interventionICU |
| spellingShingle | Marc Turon Sol Fernandez-Gonzalo Mercè Jodar Gemma Gomà Jaume Montanya David Hernando Raquel Bailón Candelaria de Haro Victor Gomez-Simon Josefina Lopez-Aguilar Rudys Magrans Melcior Martinez-Perez Joan Carles Oliva Lluís Blanch Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients Annals of Intensive Care Neurocognitive impairments Critically ill patients Neurocognitive stimulation Virtual reality Early intervention ICU |
| title | Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients |
| title_full | Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients |
| title_fullStr | Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients |
| title_full_unstemmed | Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients |
| title_short | Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients |
| title_sort | feasibility and safety of virtual reality based early neurocognitive stimulation in critically ill patients |
| topic | Neurocognitive impairments Critically ill patients Neurocognitive stimulation Virtual reality Early intervention ICU |
| url | http://link.springer.com/article/10.1186/s13613-017-0303-4 |
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