Pathological proliferation: a potential mechanism for poor CD4+ T cell recovery in people living with HIV

Pathological proliferation: a potential mechanism for poor CD4+ T cell recovery in people living with HIV

BackgroundPeople living with HIV (PLWH) fail to achieve normalization of CD4+ T cell counts and function, especially in immunological non-responders (INRs). The frequencies of Ki67+CD4+ T cells were inversely associated with CD4+ T cell counts in HIV infected patients. Early ART did not normalize CD...

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Bibliographic Details
Main Authors: Yang Zhang, Jiahao Ji, Kaidi Xie, Miaotian Cai, Rui Wang, Xin Zhang, Xue Chen, Yulin Zhang, Hao Wu, Wen Wang, Zhen Li, Tong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
pathological proliferation
immunological non-responder (INR)
CD4+ T cells
human immunodeficiency virus - HIV
mass cytometry
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1344778/full

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