Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc
PVAH is a mixture of solid and fluid, but its mechanical behavior has usually been described using solid material models. The purpose of this study was to obtain material properties that can reflect the mechanical behavior of polyvinyl alcohol hydrogel (PVAH) using finite element analysis, a biphasi...
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| Format: | Article |
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MDPI AG
2022-01-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/15/3/1125 |
| _version_ | 1797486563464052736 |
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| author | Minhyeok Heo Seonghun Park |
| author_facet | Minhyeok Heo Seonghun Park |
| author_sort | Minhyeok Heo |
| collection | DOAJ |
| description | PVAH is a mixture of solid and fluid, but its mechanical behavior has usually been described using solid material models. The purpose of this study was to obtain material properties that can reflect the mechanical behavior of polyvinyl alcohol hydrogel (PVAH) using finite element analysis, a biphasic continuum model, and to optimize the composition ratio of PVAH to replace the nucleus pulposus (NP) of the human intervertebral disc. Six types of PVAH specimens (3, 5, 7, 10, 15, 20 wt%) were prepared, then unconfined compression experiments were performed to acquire their material properties using the Holmes–Mow biphasic model. With an increasing weight percentage of PVA in PVAH, the Young’s modulus increased while the permeability parameter decreased. The Young’s modulus and permeability parameter were similar to those of the NP at 15 wt% and 20 wt%. The range of motion, facet joint force, and NP pressures measured from dynamic motional analysis of the lumbar segments with the NP model also exhibited similar values to those with 15~20 wt% PVAH models. Considering the structural stability and pain of the lumbar segments, it appears that 20 wt% PVAH is most suitable for replacing the NP. |
| first_indexed | 2024-03-09T23:35:00Z |
| format | Article |
| id | doaj.art-4cfcc6b984b04757855ab89127ff11a9 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T23:35:00Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
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| spelling | doaj.art-4cfcc6b984b04757855ab89127ff11a92023-11-23T17:02:41ZengMDPI AGMaterials1996-19442022-01-01153112510.3390/ma15031125Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral DiscMinhyeok Heo0Seonghun Park1School of Mechanical Engineering, Pusan National University, Busan 46241, KoreaSchool of Mechanical Engineering, Pusan National University, Busan 46241, KoreaPVAH is a mixture of solid and fluid, but its mechanical behavior has usually been described using solid material models. The purpose of this study was to obtain material properties that can reflect the mechanical behavior of polyvinyl alcohol hydrogel (PVAH) using finite element analysis, a biphasic continuum model, and to optimize the composition ratio of PVAH to replace the nucleus pulposus (NP) of the human intervertebral disc. Six types of PVAH specimens (3, 5, 7, 10, 15, 20 wt%) were prepared, then unconfined compression experiments were performed to acquire their material properties using the Holmes–Mow biphasic model. With an increasing weight percentage of PVA in PVAH, the Young’s modulus increased while the permeability parameter decreased. The Young’s modulus and permeability parameter were similar to those of the NP at 15 wt% and 20 wt%. The range of motion, facet joint force, and NP pressures measured from dynamic motional analysis of the lumbar segments with the NP model also exhibited similar values to those with 15~20 wt% PVAH models. Considering the structural stability and pain of the lumbar segments, it appears that 20 wt% PVAH is most suitable for replacing the NP.https://www.mdpi.com/1996-1944/15/3/1125PVAHlumbar spinebiphasic continuum modelnucleus pulposusHolmes–Mow model |
| spellingShingle | Minhyeok Heo Seonghun Park Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc Materials PVAH lumbar spine biphasic continuum model nucleus pulposus Holmes–Mow model |
| title | Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc |
| title_full | Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc |
| title_fullStr | Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc |
| title_full_unstemmed | Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc |
| title_short | Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc |
| title_sort | biphasic properties of pvah polyvinyl alcohol hydrogel reflecting biomechanical behavior of the nucleus pulposus of the human intervertebral disc |
| topic | PVAH lumbar spine biphasic continuum model nucleus pulposus Holmes–Mow model |
| url | https://www.mdpi.com/1996-1944/15/3/1125 |
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