Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery.
BACKGROUND:Hip fracture is a common health problem in the elderly that is associated with increased mortality. Acute kidney injury (AKI) is a frequent complication in elderly patients undergoing surgery and is associated with the clinical outcome. We evaluated the incidence and risk factors of AKI i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5398695?pdf=render |
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| author | Seong Eun Hong Tae-Young Kim Je-Hyun Yoo Jwa-Kyung Kim Sung Gyun Kim Hyung Jik Kim Young Rim Song |
| author_facet | Seong Eun Hong Tae-Young Kim Je-Hyun Yoo Jwa-Kyung Kim Sung Gyun Kim Hyung Jik Kim Young Rim Song |
| author_sort | Seong Eun Hong |
| collection | DOAJ |
| description | BACKGROUND:Hip fracture is a common health problem in the elderly that is associated with increased mortality. Acute kidney injury (AKI) is a frequent complication in elderly patients undergoing surgery and is associated with the clinical outcome. We evaluated the incidence and risk factors of AKI in elderly patients undergoing hip fracture surgery and the impact of AKI on short- and long-term clinical outcomes. METHODS:We performed a retrospective cohort study of 450 elderly patients who underwent hip fracture surgery between January 2010 and December 2012. We defined AKI according to the Acute Kidney Injury Network (AKIN) criteria and investigated the effect of AKI on the duration of hospital stay and in-hospital and long-term mortality. RESULTS:Of the 450 patients, 95 (21.1%) developed AKI during hospitalization and 178 (39.6%) died, with a mean follow-up of 3.6 ± 1.0 years. The baseline serum creatinine level, use of angiotensin-converting enzyme inhibitors or angiotensin-II receptor antagonists, red blood cell transfusion volume, and history of coronary artery disease were independent risk factors for AKI. Patients with AKI during hospitalization had significantly longer hospital stays and higher in-hospital and long-term mortality than those without AKI. Multivariate analysis revealed that age, history of coronary artery disease, serum albumin level, and AKI were independent predictors of long-term mortality. CONCLUSIONS:AKI is a frequent complication in elderly patients undergoing hip fracture surgery and is independently associated with increased in-hospital and long-term mortality. |
| first_indexed | 2024-12-13T21:29:46Z |
| format | Article |
| id | doaj.art-4d0651a6213d4a058d9e8fc2ccb1c95c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T21:29:46Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-4d0651a6213d4a058d9e8fc2ccb1c95c2022-12-21T23:30:51ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01124e017625910.1371/journal.pone.0176259Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery.Seong Eun HongTae-Young KimJe-Hyun YooJwa-Kyung KimSung Gyun KimHyung Jik KimYoung Rim SongBACKGROUND:Hip fracture is a common health problem in the elderly that is associated with increased mortality. Acute kidney injury (AKI) is a frequent complication in elderly patients undergoing surgery and is associated with the clinical outcome. We evaluated the incidence and risk factors of AKI in elderly patients undergoing hip fracture surgery and the impact of AKI on short- and long-term clinical outcomes. METHODS:We performed a retrospective cohort study of 450 elderly patients who underwent hip fracture surgery between January 2010 and December 2012. We defined AKI according to the Acute Kidney Injury Network (AKIN) criteria and investigated the effect of AKI on the duration of hospital stay and in-hospital and long-term mortality. RESULTS:Of the 450 patients, 95 (21.1%) developed AKI during hospitalization and 178 (39.6%) died, with a mean follow-up of 3.6 ± 1.0 years. The baseline serum creatinine level, use of angiotensin-converting enzyme inhibitors or angiotensin-II receptor antagonists, red blood cell transfusion volume, and history of coronary artery disease were independent risk factors for AKI. Patients with AKI during hospitalization had significantly longer hospital stays and higher in-hospital and long-term mortality than those without AKI. Multivariate analysis revealed that age, history of coronary artery disease, serum albumin level, and AKI were independent predictors of long-term mortality. CONCLUSIONS:AKI is a frequent complication in elderly patients undergoing hip fracture surgery and is independently associated with increased in-hospital and long-term mortality.http://europepmc.org/articles/PMC5398695?pdf=render |
| spellingShingle | Seong Eun Hong Tae-Young Kim Je-Hyun Yoo Jwa-Kyung Kim Sung Gyun Kim Hyung Jik Kim Young Rim Song Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. PLoS ONE |
| title | Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. |
| title_full | Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. |
| title_fullStr | Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. |
| title_full_unstemmed | Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. |
| title_short | Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery. |
| title_sort | acute kidney injury can predict in hospital and long term mortality in elderly patients undergoing hip fracture surgery |
| url | http://europepmc.org/articles/PMC5398695?pdf=render |
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