Lactobacillus casei Strain Shirota Alleviates Constipation in Adults by Increasing the Pipecolinic Acid Level in the Gut

Lactobacillus casei Strain Shirota Alleviates Constipation in Adults by Increasing the Pipecolinic Acid Level in the Gut

The benefits of probiotics for constipation are widely accepted, but the mechanisms involving gut metabolites are unclear. In this study, we investigated the effects of Lactobacillus casei strain Shirota (LcS) on constipated patients and revealed that a metabolite mediator is involved in the LcS-ind...

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Bibliographic Details
Main Authors: Yangwenshan Ou, Shanbin Chen, Fazheng Ren, Ming Zhang, Shaoyang Ge, Huiyuan Guo, Hao Zhang, Liang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
Lactobacillus casei strain Shirota
constipation
metabolomics
gut metabolites
pipecolinic acid
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00324/full

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