Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia
Aim. To assess efficacy of different methods of iodine prophylaxis in pregnant women living in conditions of goiter endemia. Material and methods. Standard clinical, laboratory and device tests for iodine deficiency according to WHO criteria were made in 156 pregnant women living in the territory af...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2003-10-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/29668 |
| _version_ | 1819171287806771200 |
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| author | Е F Turovinina L A Suplotova E В Khramova S A Smetanina |
| author_facet | Е F Turovinina L A Suplotova E В Khramova S A Smetanina |
| author_sort | Е F Turovinina |
| collection | DOAJ |
| description | Aim. To assess efficacy of different methods of iodine prophylaxis in pregnant women living in conditions of goiter endemia.
Material and methods. Standard clinical, laboratory and device tests for iodine deficiency according
to WHO criteria were made in 156 pregnant women living in the territory affected by goiter endemia.
Of them, 121 examinees had no thyroid pathology, 35 ones had diffuse euthyroid goiter. All of them
received different kinds of iodine prophylaxis.
Results. The occurrence of neonatal TTH values over 5 iU/l in neonates born by mothers free of thyroid pathology on potassium iodide prophylaxis when pregnant was 9.1%. This is much lower than in
conventional iodine prophylaxis - 17.24% (p < 0.01). A comparative analysis of the efficacy of potassium iodide-200 in pregnant women with diffuse euthyroid goiter and its combination with L-thy
roxin has shown that by the effect on lessening frequency of neonatal ТТЯ over 5 Ш/l the above
schemes do not differ significantly, thyroid reduction is more prominent in pregnant women on thyroxine with potassium iodide.
Conclusion. The index of neonatal TTH is an objective criterium to control efficacy of different methods of iodine prophylaxis in pregnancy. |
| first_indexed | 2024-12-22T19:48:54Z |
| format | Article |
| id | doaj.art-4d0cdb04d7884c4f8fb2f624d972d240 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-22T19:48:54Z |
| publishDate | 2003-10-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-4d0cdb04d7884c4f8fb2f624d972d2402022-12-21T18:14:36Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422003-10-017810545626696Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemiaЕ F TurovininaL A SuplotovaE В KhramovaS A SmetaninaAim. To assess efficacy of different methods of iodine prophylaxis in pregnant women living in conditions of goiter endemia. Material and methods. Standard clinical, laboratory and device tests for iodine deficiency according to WHO criteria were made in 156 pregnant women living in the territory affected by goiter endemia. Of them, 121 examinees had no thyroid pathology, 35 ones had diffuse euthyroid goiter. All of them received different kinds of iodine prophylaxis. Results. The occurrence of neonatal TTH values over 5 iU/l in neonates born by mothers free of thyroid pathology on potassium iodide prophylaxis when pregnant was 9.1%. This is much lower than in conventional iodine prophylaxis - 17.24% (p < 0.01). A comparative analysis of the efficacy of potassium iodide-200 in pregnant women with diffuse euthyroid goiter and its combination with L-thy roxin has shown that by the effect on lessening frequency of neonatal ТТЯ over 5 Ш/l the above schemes do not differ significantly, thyroid reduction is more prominent in pregnant women on thyroxine with potassium iodide. Conclusion. The index of neonatal TTH is an objective criterium to control efficacy of different methods of iodine prophylaxis in pregnancy.https://ter-arkhiv.ru/0040-3660/article/view/29668pregnancyprevention of iodine deficiencydiffuse euthyroid goiterpotassium iodidethyroxine |
| spellingShingle | Е F Turovinina L A Suplotova E В Khramova S A Smetanina Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia Терапевтический архив pregnancy prevention of iodine deficiency diffuse euthyroid goiter potassium iodide thyroxine |
| title | Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| title_full | Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| title_fullStr | Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| title_full_unstemmed | Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| title_short | Iodine prophylaxis in pregnant women: a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| title_sort | iodine prophylaxis in pregnant women a comparativeanalysis of different methods efficacy in conditions of goiter endemia |
| topic | pregnancy prevention of iodine deficiency diffuse euthyroid goiter potassium iodide thyroxine |
| url | https://ter-arkhiv.ru/0040-3660/article/view/29668 |
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