Esketamine-based opioid-free anaesthesia alleviates postoperative nausea and vomiting in patients who underwent laparoscopic surgery: study protocol for a randomized, double-blinded, multicentre trial

Esketamine-based opioid-free anaesthesia alleviates postoperative nausea and vomiting in patients who underwent laparoscopic surgery: study protocol for a randomized, double-blinded, multicentre trial

Abstract Background Although opioids are commonly prescribed in clinical anaesthesia, the significant side effects attributed to their overuse are raising increasing concerns. One way to reduce perioperative opioid consumption is to apply opioid-reduced anaesthesia (ORA) and even opioid-free anaesth...

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Bibliographic Details
Main Authors: Hai-yan Chen, Xiao-yan Meng, Hao Gao, Hui Liu, Hai-Bo Qiu, Jun Lu, Jin-Chao Song
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Trials
Subjects:
Esketamine
Opioid-free anaesthesia
Postoperative nausea and vomiting
Online Access:https://doi.org/10.1186/s13063-022-07003-3

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