Faecal microbiome-based machine learning for multi-class disease diagnosis

Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive diagnostics and monitor responses to therapy.

Bibliographic Details
Main Authors: Qi Su, Qin Liu, Raphaela Iris Lau, Jingwan Zhang, Zhilu Xu, Yun Kit Yeoh, Thomas W. H. Leung, Whitney Tang, Lin Zhang, Jessie Q. Y. Liang, Yuk Kam Yau, Jiaying Zheng, Chengyu Liu, Mengjing Zhang, Chun Pan Cheung, Jessica Y. L. Ching, Hein M. Tun, Jun Yu, Francis K. L. Chan, Siew C. Ng
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34405-3
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author Qi Su
Qin Liu
Raphaela Iris Lau
Jingwan Zhang
Zhilu Xu
Yun Kit Yeoh
Thomas W. H. Leung
Whitney Tang
Lin Zhang
Jessie Q. Y. Liang
Yuk Kam Yau
Jiaying Zheng
Chengyu Liu
Mengjing Zhang
Chun Pan Cheung
Jessica Y. L. Ching
Hein M. Tun
Jun Yu
Francis K. L. Chan
Siew C. Ng
author_facet Qi Su
Qin Liu
Raphaela Iris Lau
Jingwan Zhang
Zhilu Xu
Yun Kit Yeoh
Thomas W. H. Leung
Whitney Tang
Lin Zhang
Jessie Q. Y. Liang
Yuk Kam Yau
Jiaying Zheng
Chengyu Liu
Mengjing Zhang
Chun Pan Cheung
Jessica Y. L. Ching
Hein M. Tun
Jun Yu
Francis K. L. Chan
Siew C. Ng
author_sort Qi Su
collection DOAJ
description Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive diagnostics and monitor responses to therapy.
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spelling doaj.art-4d13f20fc0364cfc832e975f3b7201d32022-12-22T02:31:10ZengNature PortfolioNature Communications2041-17232022-11-011311810.1038/s41467-022-34405-3Faecal microbiome-based machine learning for multi-class disease diagnosisQi Su0Qin Liu1Raphaela Iris Lau2Jingwan Zhang3Zhilu Xu4Yun Kit Yeoh5Thomas W. H. Leung6Whitney Tang7Lin Zhang8Jessie Q. Y. Liang9Yuk Kam Yau10Jiaying Zheng11Chengyu Liu12Mengjing Zhang13Chun Pan Cheung14Jessica Y. L. Ching15Hein M. Tun16Jun Yu17Francis K. L. Chan18Siew C. Ng19Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Department of Medicine and Therapeutics, The Chinese University of Hong KongMicrobiota I-Center (MagIC)Microbiota I-Center (MagIC)Department of Medicine and Therapeutics, The Chinese University of Hong KongMicrobiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Microbiota I-Center (MagIC)Department of Medicine and Therapeutics, The Chinese University of Hong KongMicrobiota I-Center (MagIC)Microbiota I-Center (MagIC)Here, using fecal metagenomics data of 2,320 individuals, the authors develop a microbiome-based machine learning approach showing high accuracy for multi-class disease diagnosis, highlighting its potential application in improving noninvasive diagnostics and monitor responses to therapy.https://doi.org/10.1038/s41467-022-34405-3
spellingShingle Qi Su
Qin Liu
Raphaela Iris Lau
Jingwan Zhang
Zhilu Xu
Yun Kit Yeoh
Thomas W. H. Leung
Whitney Tang
Lin Zhang
Jessie Q. Y. Liang
Yuk Kam Yau
Jiaying Zheng
Chengyu Liu
Mengjing Zhang
Chun Pan Cheung
Jessica Y. L. Ching
Hein M. Tun
Jun Yu
Francis K. L. Chan
Siew C. Ng
Faecal microbiome-based machine learning for multi-class disease diagnosis
Nature Communications
title Faecal microbiome-based machine learning for multi-class disease diagnosis
title_full Faecal microbiome-based machine learning for multi-class disease diagnosis
title_fullStr Faecal microbiome-based machine learning for multi-class disease diagnosis
title_full_unstemmed Faecal microbiome-based machine learning for multi-class disease diagnosis
title_short Faecal microbiome-based machine learning for multi-class disease diagnosis
title_sort faecal microbiome based machine learning for multi class disease diagnosis
url https://doi.org/10.1038/s41467-022-34405-3
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