Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning
The widespread use of diquat as a substitute for paraquat has led to an increase in poisoning deaths. A successful case of diquat poisoning complicated with rhabdomyolysis and shock was lacking. A 13-year-old previously healthy girl ingested 40 ml of diquat solution in a suicide attempt. The concent...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1116912/full |
| _version_ | 1811173468129984512 |
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| author | Yunchao Chen Zejin Ou Ruichang Zhang Zhenhong Long Rushen Fu Shihao Tang Zhi Wang |
| author_facet | Yunchao Chen Zejin Ou Ruichang Zhang Zhenhong Long Rushen Fu Shihao Tang Zhi Wang |
| author_sort | Yunchao Chen |
| collection | DOAJ |
| description | The widespread use of diquat as a substitute for paraquat has led to an increase in poisoning deaths. A successful case of diquat poisoning complicated with rhabdomyolysis and shock was lacking. A 13-year-old previously healthy girl ingested 40 ml of diquat solution in a suicide attempt. The concentration of diquat in serum was 436.2 ug/L at 10 h after poisoning. The clinical course was characterized by progressive multi-organ dysfunction, particularly rhabdomyolysis and shock. The main treatments included intensive hemoperfusion combined with continuous renal replacement therapy (CRRT), drainage, and activated carbon adsorption. Meanwhile, accurate dilatation under the model of pulse indicator continuous cardiac output (PICCO) was essential for the successful treatment of shock. The serum concentration of diquat declined to 20 ug/L after 96 h of treatments. The patient was discharged from the hospital after 3 weeks of treatment without obvious symptoms. So far, this was the first successful case of diquat poisoning complicated with rhabdomyolysis and shock, which would enrich the experience of diquat poisoning treatment. |
| first_indexed | 2024-04-10T17:47:27Z |
| format | Article |
| id | doaj.art-4d1a6805a9c7472f9cb9f964f6664784 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T17:47:27Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-4d1a6805a9c7472f9cb9f964f66647842023-02-03T04:55:07ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-02-011010.3389/fmed.2023.11169121116912Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoningYunchao Chen0Zejin Ou1Ruichang Zhang2Zhenhong Long3Rushen Fu4Shihao Tang5Zhi Wang6Department of Intensive Care Unit, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaDepartment of Intensive Care Unit, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaDepartment of Intensive Care Unit, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaDepartment of Intensive Care Unit, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People’s Hospital, Guangzhou, ChinaThe widespread use of diquat as a substitute for paraquat has led to an increase in poisoning deaths. A successful case of diquat poisoning complicated with rhabdomyolysis and shock was lacking. A 13-year-old previously healthy girl ingested 40 ml of diquat solution in a suicide attempt. The concentration of diquat in serum was 436.2 ug/L at 10 h after poisoning. The clinical course was characterized by progressive multi-organ dysfunction, particularly rhabdomyolysis and shock. The main treatments included intensive hemoperfusion combined with continuous renal replacement therapy (CRRT), drainage, and activated carbon adsorption. Meanwhile, accurate dilatation under the model of pulse indicator continuous cardiac output (PICCO) was essential for the successful treatment of shock. The serum concentration of diquat declined to 20 ug/L after 96 h of treatments. The patient was discharged from the hospital after 3 weeks of treatment without obvious symptoms. So far, this was the first successful case of diquat poisoning complicated with rhabdomyolysis and shock, which would enrich the experience of diquat poisoning treatment.https://www.frontiersin.org/articles/10.3389/fmed.2023.1116912/fulldiquatmulti-organ dysfunctionrhabdomyolysisshockpulse indicator continuous cardiac output |
| spellingShingle | Yunchao Chen Zejin Ou Ruichang Zhang Zhenhong Long Rushen Fu Shihao Tang Zhi Wang Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning Frontiers in Medicine diquat multi-organ dysfunction rhabdomyolysis shock pulse indicator continuous cardiac output |
| title | Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| title_full | Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| title_fullStr | Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| title_full_unstemmed | Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| title_short | Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| title_sort | case report successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning |
| topic | diquat multi-organ dysfunction rhabdomyolysis shock pulse indicator continuous cardiac output |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1116912/full |
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