Spectral Library-Based Single-Cell Proteomics Resolves Cellular Heterogeneity

Spectral Library-Based Single-Cell Proteomics Resolves Cellular Heterogeneity

Dissecting the proteome of cell types and states at single-cell resolution, while being highly challenging, has significant implications in basic science and biomedicine. Mass spectrometry (MS)-based single-cell proteomics represents an emerging technology for system-wide, unbiased profiling of prot...

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Bibliographic Details
Main Authors: Lakmini Senavirathna, Cheng Ma, Ru Chen, Sheng Pan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
single-cell proteomics
proteomics
mass spectrometry
spectral library
cellular heterogeneity
systems biology
Online Access:https://www.mdpi.com/2073-4409/11/15/2450

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